Literature DB >> 21262171

[New treatment options for primary immune thrombocytopenia].

Sif Gudbrandsdottir1, Henrik Frederiksen, Henrik Sverre Birgens, Claus Henrik Nielsen, Ove Juul Nielsen, Jesper Stentoft, Hans Carl Hasselbalch.   

Abstract

Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathogenesis of ITP. This article aims to provide an overview of current treatment options, with particular emphasis on new biological therapies: rituximab, a monoclonal anti-CD20 antibody, and the thrombopoietin receptor agonists romiplostim and eltrombopag.

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Year:  2011        PMID: 21262171

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  1 in total

1.  Thromboembolic events secondary to tirofiban-induced thrombocytopenia being treated with thrombopoietin: A case report.

Authors:  Yanhua Li; Qiang Xu; Xinhong Guo
Journal:  Exp Ther Med       Date:  2016-06-08       Impact factor: 2.447

  1 in total

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