Literature DB >> 21261647

Neuroprotective properties of resveratrol and derivatives.

Tristan Richard1, Alison D Pawlus, Marie-Laure Iglésias, Eric Pedrot, Pierre Waffo-Teguo, Jean-Michel Mérillon, Jean-Pierre Monti.   

Abstract

Stilbenoid compounds consist of a family of resveratrol derivatives. They have demonstrated promising activities in vitro and in vivo that indicate they may be useful in the prevention of a wide range of pathologies, such as cardiovascular diseases and cancers, as well have anti-aging effects. More recently stilbenoid compounds have shown promise in the treatment and prevention of neurodegenerative disorders, such as Huntington's, Parkinson's, and Alzheimer's diseases. This paper primarily focuses on the impact of stilbenoids in Alzheimer's disease and more specifically on the inhibition of β-amyloid peptide aggregation.
© 2011 New York Academy of Sciences.

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Year:  2011        PMID: 21261647     DOI: 10.1111/j.1749-6632.2010.05865.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  52 in total

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