Zheng Zhou1, Jiadong Wang, Xin Li. 1. Department of Otolaryngology-Head and Neck Surgery, Renji Hospital, Shanghai Jiaotong University, Shanghai 200001, China.
Abstract
OBJECTIVE: To determine the correlative factors on recurrent laryngeal nerve (RLN) injuries caused by ultrasonically activated shears (UAS). METHOD: Fifteen New Zealand rabbits (thirty recurrent laryngeal nerves) were randomly divided into 5 groups: group 1 and group 2 are those UAS works 1 mm away from RLN for 2 s and 4s separately, group 3 and group 4 are those UAS works 3 mm away from RLN for 2 s and 4 s separately, and the other one is control group. Electrophysiology was detected in each group. The RLN injuries of group 2, 3 and control group were observed with electron microscope. RESULT: Significant differences on amplitude and latency were found in all the experimental groups except group 3 when compared to the control group, and between every two experimental groups as well. Histological changes such as obviously swelling myelin lamellar, loosen and disordered structures, bubble-liked axon collapse and liquefaction of axoplasm were only observed in group 2. CONCLUSION: UAS is a new apparatus for cutting and coagulating in operations, which is safe and reliable to be applied for endoscopic surgery. It will be a new choice for treating thyroid neoplasm.
OBJECTIVE: To determine the correlative factors on recurrent laryngeal nerve (RLN) injuries caused by ultrasonically activated shears (UAS). METHOD: Fifteen New Zealand rabbits (thirty recurrent laryngeal nerves) were randomly divided into 5 groups: group 1 and group 2 are those UAS works 1 mm away from RLN for 2 s and 4s separately, group 3 and group 4 are those UAS works 3 mm away from RLN for 2 s and 4 s separately, and the other one is control group. Electrophysiology was detected in each group. The RLN injuries of group 2, 3 and control group were observed with electron microscope. RESULT: Significant differences on amplitude and latency were found in all the experimental groups except group 3 when compared to the control group, and between every two experimental groups as well. Histological changes such as obviously swelling myelin lamellar, loosen and disordered structures, bubble-liked axon collapse and liquefaction of axoplasm were only observed in group 2. CONCLUSION:UAS is a new apparatus for cutting and coagulating in operations, which is safe and reliable to be applied for endoscopic surgery. It will be a new choice for treating thyroid neoplasm.