Literature DB >> 21258810

Prevention of post-operative infections in spine surgery by wound irrigation with a solution of povidone-iodine and hydrogen peroxide.

Simone Ulivieri1, Stefano Toninelli, Carlo Petrini, Antonio Giorgio, Giuseppe Oliveri.   

Abstract

INTRODUCTION: Starting from January 2009, we systematically irrigated the surgical wounds of patients undergoing spine surgery with a solution of povidone-iodine (PVP-I) and hydrogen peroxide (H(2)O(2)).
METHOD: We prospectively recorded the clinical data of patients who underwent spine surgery during 2009 and we compared the results with retrospectively reviewed clinical records of patients operated during 2008. Patients were analyzed for preoperative risk factors, type of surgical procedure, onset of the infection, clinical presentation, treatment, and outcome. We performed 460 spine surgeries during 2008 and 490 during 2009.
RESULTS: We recorded seven post-operative infections in 2008 compared to none in 2009.
CONCLUSION: We consider the solution of PVP-I plus H(2)O(2) effective in further reducing the rate of post-operative infection in spine surgery.

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Year:  2011        PMID: 21258810     DOI: 10.1007/s00402-011-1262-0

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  11 in total

1.  Co-operative inhibitory effects of hydrogen peroxide and iodine against bacterial and yeast species.

Authors:  Elena I Zubko; Mikhajlo K Zubko
Journal:  BMC Res Notes       Date:  2013-07-15

2.  Multidisciplinary intensive care in extensive necrotizing fasciitis.

Authors:  Guo-Wei Tu; J O Hwabejire; Min-Jie Ju; Yuan-Feng Yang; Guang-Jian Zhang; Jian-Wei Xu; Zhang-Gang Xue; Chun Jiang; C Jiang; Zhe Luo; Z Luo
Journal:  Infection       Date:  2012-10-27       Impact factor: 3.553

3.  The Effects of Rifampin, Povidone-Iodine and Hydrogen Peroxide on the Formation of Epidural Fibrosis in the Experimental Epidural Fibrosis Model.

Authors:  Zahir Kizilay; Nesibe Kahraman Cetin; Özgur İsmailoglu; Ali Yılmaz; İmran Kurt Omurlu; Mehmet Erdal Coskun; Serdar Aktaş
Journal:  Inflammation       Date:  2016-08       Impact factor: 4.092

4.  Histopathological changes of neuronal tissue following the use of hydrogen peroxide in neurosurgical procedures.

Authors:  Mohammad M Alshardan; Abdullah M Abunimer; Hussam Abou-Al-Shaar; Sadeq Aldandan; Sherif M El-Watidy; Ali M Mustafa; Abdulrahman J Sabbagh
Journal:  Surg Neurol Int       Date:  2021-03-08

Review 5.  Hydrogen Peroxide Wound Irrigation in Orthopaedic Surgery.

Authors:  Min Lu; Erik Nathan Hansen
Journal:  J Bone Jt Infect       Date:  2017-01-01

Review 6.  Intrawound Treatment for Prevention of Surgical Site Infections in Instrumented Spinal Surgery: A Systematic Comparative Effectiveness Review and Meta-Analysis.

Authors:  Justin V C Lemans; Sebastiaan P J Wijdicks; Willemijn Boot; Geertje A M Govaert; R Marijn Houwert; F Cumhur Öner; Moyo C Kruyt
Journal:  Global Spine J       Date:  2018-07-26

7.  Cell Toxicity Study of Antiseptic Solutions Containing Povidone-Iodine and Hydrogen Peroxide.

Authors:  Veronica Romano; Donato Di Gennaro; Anna Maria Sacco; Enrico Festa; Emanuela Roscetto; Morena Anna Basso; Tiziana Ascione; Giovanni Balato
Journal:  Diagnostics (Basel)       Date:  2022-08-21

8.  Irrigation Solutions in Total Joint Arthroplasty.

Authors:  Matthew Caid; Josiah Valk; Jonathan Danoff
Journal:  Spartan Med Res J       Date:  2022-09-06

9.  [Effect of hydrogen peroxide on anti-infection and reducing postoperative drainage in multi-segmental lumbar surgery].

Authors:  Hao Chen; Junsong Yang; Tuanjiang Liu; Ye Tian; Keyuan Ding; Yumin Zhou; Dageng Huang; Dingjun Hao
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2020-03-15

Review 10.  Wound irrigation for preventing surgical site infections.

Authors:  Marios Papadakis
Journal:  World J Methodol       Date:  2021-07-20
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