Literature DB >> 21258698

A rational approach to tuning the pKa values of rhodamines for living cell fluorescence imaging.

Lin Yuan1, Weiying Lin, Yanming Feng.   

Abstract

A novel strategy to systematically tune the pK(a) values of rhodamines is described. This strategy was applied to rationally develop compound 1e with a pK(a) of 6.5, the highest among rhodamine amide derivatives, and it could be employed to detect acidic pH variations in living cells with a turn-on signal.

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Year:  2011        PMID： 21258698     DOI： 10.1039/c0ob01045f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  10 in total

1.  Development of a Nile-blue based chemodosimeter for Hg2+ in aqueous solution and its application in biological imaging.

Authors:  Mingming Hu; Jianhua Yin; Yahong Li; Xiaofang Zhao
Journal:  J Fluoresc       Date:  2015-02-10       Impact factor: 2.217

2.  Fluorescent probes with high pKa values based on traditional, near-infrared rhodamine, and hemicyanine fluorophores for sensitive detection of lysosomal pH variations.

Authors:  Wafa Mazi; Rashmi Adhikari; Yibin Zhang; Shuai Xia; Mingxi Fang; Rudy L Luck; Momoko Tajiri; Ashutosh Tiwari; Marina Tanasova; Haiying Liu
Journal:  Methods       Date:  2019-07-22       Impact factor: 3.608

3.  pH Effect on Two-Photon Cross Section of Highly Fluorescent Dyes Using Femtosecond Two-Photon Induced Fluorescence.

Authors:  Krishnandu Makhal; Debabrata Goswami
Journal:  J Fluoresc       Date:  2016-11-15       Impact factor: 2.217

4.  Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications.

Authors:  Andreas Steinegger; Otto S Wolfbeis; Sergey M Borisov
Journal:  Chem Rev       Date:  2020-11-04       Impact factor: 60.622

5.  Cycloalkyl-aminomethylrhodamines: pH dependent photophysical properties tuned by cycloalkane ring size.

Authors:  Chuangjun Liu; Quinn A Best; Brian Suarez; Jack Pertile; Matthew E McCarroll; Colleen N Scott
Journal:  J Fluoresc       Date:  2015-02-17       Impact factor: 2.217

6.  A library of Rhodamine6G-based pH-sensitive fluorescent probes with versatile in vivo and in vitro applications.

Authors:  W Benton Swanson; Margaret Durdan; Miranda Eberle; Seth Woodbury; Ava Mauser; Jason Gregory; Boya Zhang; David Niemann; Jacob Herremans; Peter X Ma; Joerg Lahann; Megan Weivoda; Yuji Mishina; Colin F Greineder
Journal:  RSC Chem Biol       Date:  2022-04-29

7.  Rhodamine-based Cu2+-selective fluorosensor: synthesis, mechanism, and application in living cells.

Authors:  Anindita Sikdar; Swapnadip Roy; Kakali Haldar; Soma Sarkar; Sujit S Panja
Journal:  J Fluoresc       Date:  2013-02-10       Impact factor: 2.217

8.  A DNA-based fluorescent reporter maps HOCl production in the maturing phagosome.

Authors:  Shareefa Thekkan; Maulik S Jani; Chang Cui; Krishna Dan; Guolin Zhou; Lev Becker; Yamuna Krishnan
Journal:  Nat Chem Biol       Date:  2018-12-10       Impact factor: 15.040

9.  New fluorescent pH sensors based on covalently linkable PET rhodamines.

Authors:  Daniel Aigner; Sergey M Borisov; Francisco J Orriach Fernández; Jorge F Fernández Sánchez; Robert Saf; Ingo Klimant
Journal:  Talanta       Date:  2012-05-26       Impact factor: 6.057

10.  H-Rubies, a new family of red emitting fluorescent pH sensors for living cells.

Authors:  Guillaume Despras; Alsu I Zamaleeva; Lucie Dardevet; Céline Tisseyre; Joao Gamelas Magalhaes; Charlotte Garner; Michel De Waard; Sebastian Amigorena; Anne Feltz; Jean-Maurice Mallet; Mayeul Collot
Journal:  Chem Sci       Date:  2015-07-14       Impact factor: 9.825
  10 in total

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