AIM: To investigate the safety of consecutive mini-laparoscopy guided liver biopsies for the diagnosis and staging of liver diseases. METHODS: In this study we retrospectively analyzed the safety of mini-laparoscopic liver biopsy performed in an endoscopy unit in 1071 patients. We measured the incidence of bleeding and evaluated the management and outcome of bleeding interventions. RESULTS: The most common etiologies of liver injury were viral hepatitis and autoimmune liver disease. 250 patients had macroscopically and histologically proven cirrhosis. 13 patients had no pathological findings. 33% of all patients had bleeding that required argon plasma coagulation of the puncture site during laparoscopy. Significant bleeding occurred more often in patients with liver cirrhosis compared to non-cirrhotic liver diseases but was effectively treated with laparoscopic coagulation. CONCLUSION: In conclusion, mini-laparoscopy liver biopsy can be performed safely and effectively in high risk patients with advanced liver disease; mini-laparoscopy with liver biopsy can be done safely in an endoscopy unit.
AIM: To investigate the safety of consecutive mini-laparoscopy guided liver biopsies for the diagnosis and staging of liver diseases. METHODS: In this study we retrospectively analyzed the safety of mini-laparoscopic liver biopsy performed in an endoscopy unit in 1071 patients. We measured the incidence of bleeding and evaluated the management and outcome of bleeding interventions. RESULTS: The most common etiologies of liver injury were viral hepatitis and autoimmune liver disease. 250 patients had macroscopically and histologically proven cirrhosis. 13 patients had no pathological findings. 33% of all patients had bleeding that required argon plasma coagulation of the puncture site during laparoscopy. Significant bleeding occurred more often in patients with liver cirrhosis compared to non-cirrhotic liver diseases but was effectively treated with laparoscopic coagulation. CONCLUSION: In conclusion, mini-laparoscopy liver biopsy can be performed safely and effectively in high risk patients with advanced liver disease; mini-laparoscopy with liver biopsy can be done safely in an endoscopy unit.
Authors: Kelly A Gebo; H Franklin Herlong; Michael S Torbenson; Mollie W Jenckes; Geetanjali Chander; Khalil G Ghanem; Samer S El-Kamary; Mark Sulkowski; Eric B Bass Journal: Hepatology Date: 2002-11 Impact factor: 17.425
Authors: K R Reddy; J Levi; A Livingstone; L Jeffers; E Molina; S Kligerman; D Bernstein; V P Kodali; E R Schiff Journal: Gastrointest Endosc Date: 1999-04 Impact factor: 9.427
Authors: Christopher J Barreiro; Keith D Lillemoe; Leonidas G Koniaris; Taylor A Sohn; Charles J Yeo; JoAnn Coleman; Elliot K Fishman; John L Cameron Journal: J Gastrointest Surg Date: 2002 Jan-Feb Impact factor: 3.452
Authors: I Helmreich-Becker; P Schirmacher; U Denzer; A Hensel; K H Meyer zum Büschenfelde; A W Lohse Journal: Endoscopy Date: 2003-01 Impact factor: 10.093