Johan Mathillas1, Hugo Lövheim, Yngve Gustafson. 1. Geriatric Medicine, Department of Community Medicine and Rehabilitation, Umeå University, Umeå SE-901 85, Sweden. johan.mathillas@germed.umu.se
Abstract
BACKGROUND: it is unknown whether the age-specific prevalence of dementia among the very old changes over time. METHODS: this study compares the prevalence of dementia in two population-based cross-sectional samples of very old people in northern Sweden in 2000-02 and in 2005-07. In total, 430 individuals aged 85 and older (mean age 89.5 years, 71.4% women) were evaluated for dementia in the first cross-section and 465 individuals (mean age 90.2 years, 70.9% women) in the second. Trained assessors performed assessments and interviews during home visits and collected information from carers, relatives and medical records. Dementia was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. RESULTS: the prevalence of dementia in the total sample was 26.5% in 2000-02 and 37.2% in 2005-07 (P = 0.001). There was also an increase in the prescription of different antihypertensive agents, antilipemic agents and choline esterase inhibitors, and more people had had heart surgery in the later sample. CONCLUSIONS: in this sample of very old people, an increase in the age-specific prevalence of dementia was detected over 5 years. Possible reasons for this may be extended survival among individuals with risk factors for dementia and among individuals with established dementia.
BACKGROUND: it is unknown whether the age-specific prevalence of dementia among the very old changes over time. METHODS: this study compares the prevalence of dementia in two population-based cross-sectional samples of very old people in northern Sweden in 2000-02 and in 2005-07. In total, 430 individuals aged 85 and older (mean age 89.5 years, 71.4% women) were evaluated for dementia in the first cross-section and 465 individuals (mean age 90.2 years, 70.9% women) in the second. Trained assessors performed assessments and interviews during home visits and collected information from carers, relatives and medical records. Dementia was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. RESULTS: the prevalence of dementia in the total sample was 26.5% in 2000-02 and 37.2% in 2005-07 (P = 0.001). There was also an increase in the prescription of different antihypertensive agents, antilipemic agents and choline esterase inhibitors, and more people had had heart surgery in the later sample. CONCLUSIONS: in this sample of very old people, an increase in the age-specific prevalence of dementia was detected over 5 years. Possible reasons for this may be extended survival among individuals with risk factors for dementia and among individuals with established dementia.
Authors: Claudia L Satizabal; Alexa S Beiser; Vincent Chouraki; Geneviève Chêne; Carole Dufouil; Sudha Seshadri Journal: N Engl J Med Date: 2016-02-11 Impact factor: 91.245
Authors: Helena Claesson Lingehall; Nina S Smulter; Elisabeth Lindahl; Marie Lindkvist; Karl Gunnar Engström; Yngve G Gustafson; Birgitta Olofsson Journal: Crit Care Med Date: 2017-08 Impact factor: 7.598
Authors: Antoneta Granic; Karen Davies; Ashley Adamson; Thomas Kirkwood; Tom R Hill; Mario Siervo; John C Mathers; Carol Jagger Journal: J Nutr Date: 2016-01-06 Impact factor: 4.798