Literature DB >> 21257780

Coup d'Etat: an orphan takes control.

Fu-Jung Lin1, Jun Qin, Ke Tang, Sophia Y Tsai, Ming-Jer Tsai.   

Abstract

Chicken ovalbumin upstream promoter transcription factors (COUP-TFs) belong to the steroid/thyroid hormone receptor superfamily. Cloning of their cDNAs demonstrated the existence of two distinct but related genes: COUP-TFI (EAR-3, NR2F1) and COUP-TFII (ARP-1, NR2F2). They are referred to as orphan receptors because ligands for COUP-TFs have yet to be identified. Since 1998, extensive studies have demonstrated their physiological importance in cell-fate specification, organogenesis, angiogenesis, and metabolism, as well as a variety of diseases. In this article, we will comprehensively review the biological functions of COUP-TFII and its underlying mechanism in various developmental processes and diseases. In addition, we will briefly summarize some of the current findings of COUP-TFI.

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Year:  2011        PMID： 21257780      PMCID： PMC3365794          DOI： 10.1210/er.2010-0021

Source DB:  PubMed          Journal:  Endocr Rev        ISSN： 0163-769X            Impact factor:   19.871


  103 in total

Review 1.  Genetic regulation of cerebellar development.

Authors:  V Y Wang; H Y Zoghbi
Journal:  Nat Rev Neurosci       Date:  2001-07       Impact factor: 34.870

2.  COUP-TFI: an intrinsic factor for early regionalization of the neocortex.

Authors:  C Zhou; S Y Tsai; M J Tsai
Journal:  Genes Dev       Date:  2001-08-15       Impact factor: 11.361

3.  COUP-TFI (chicken ovalbumin upstream promoter-transcription factor I) regulates cell migration and axogenesis in differentiating P19 embryonal carcinoma cells.

Authors:  F Adam; T Sourisseau; R Métivier; Y Le Page; C Desbois; D Michel; G Salbert
Journal:  Mol Endocrinol       Date:  2000-12

4.  Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter.

Authors:  V Krishnan; G Elberg; M J Tsai; S Y Tsai
Journal:  Mol Endocrinol       Date:  1997-09

5.  Arteriovenous malformations in mice lacking activin receptor-like kinase-1.

Authors:  L D Urness; L K Sorensen; D Y Li
Journal:  Nat Genet       Date:  2000-11       Impact factor: 38.330

6.  Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression.

Authors:  C M Klinge; B F Silver; M D Driscoll; G Sathya; R A Bambara; R Hilf
Journal:  J Biol Chem       Date:  1997-12-12       Impact factor: 5.157

7.  Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase.

Authors:  V Krishnan; F A Pereira; Y Qiu; C H Chen; P A Beachy; S Y Tsai; M J Tsai
Journal:  Science       Date:  1997-12-12       Impact factor: 47.728

8.  Deletion 15q24-26 in prenatally detected diaphragmatic hernia: increasing evidence of a candidate region for diaphragmatic development.

Authors:  D Schlembach; M Zenker; U Trautmann; R Ulmer; E Beinder
Journal:  Prenat Diagn       Date:  2001-04       Impact factor: 3.050

9.  Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4.

Authors:  H U Wang; Z F Chen; D J Anderson
Journal:  Cell       Date:  1998-05-29       Impact factor: 41.582

10.  Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

Authors:  N D Lawson; N Scheer; V N Pham; C H Kim; A B Chitnis; J A Campos-Ortega; B M Weinstein
Journal:  Development       Date:  2001-10       Impact factor: 6.868
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  79 in total

1.  Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression.

Authors:  Sandra Mayer; Marc Roeser; Peter Lachmann; Sumiyashi Ishii; Jae Mi Suh; Sabine Harlander; Michael Desch; Coy Brunssen; Henning Morawietz; Sophia Y Tsai; Ming-Jer Tsai; Bernd Hohenstein; Christian Hugo; Vladimir T Todorov
Journal:  J Biol Chem       Date:  2012-05-29       Impact factor: 5.157

Review 2.  Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration.

Authors:  Goldis Malek; Eleonora M Lad
Journal:  Cell Mol Life Sci       Date:  2014-08-26       Impact factor: 9.261

Review 3.  The orphan nuclear receptors at their 25-year reunion.

Authors:  Shannon E Mullican; Joanna R Dispirito; Mitchell A Lazar
Journal:  J Mol Endocrinol       Date:  2013-11-26       Impact factor: 5.098

Review 4.  Human genetic variation within neural crest enhancers: molecular and phenotypic implications.

Authors:  Alvaro Rada-Iglesias; Sara L Prescott; Joanna Wysocka
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-05-06       Impact factor: 6.237

5.  COUP-TFII regulates human endometrial stromal genes involved in inflammation.

Authors:  Xilong Li; Michael J Large; Chad J Creighton; Rainer B Lanz; Jae-Wook Jeong; Steven L Young; Bruce A Lessey; Wilder A Palomino; Sophia Y Tsai; Francesco J Demayo
Journal:  Mol Endocrinol       Date:  2013-10-31

Review 6.  Nuclear receptors in neural stem/progenitor cell homeostasis.

Authors:  Dimitrios Gkikas; Matina Tsampoula; Panagiotis K Politis
Journal:  Cell Mol Life Sci       Date:  2017-06-21       Impact factor: 9.261

Review 7.  COUP-TFII revisited: Its role in metabolic gene regulation.

Authors:  Usman M Ashraf; Edwin R Sanchez; Sivarajan Kumarasamy
Journal:  Steroids       Date:  2018-11-24       Impact factor: 2.668

8.  Estradiol differentially regulates calreticulin: a potential link with abnormal T cell function in systemic lupus erythematosus?

Authors:  J M Ward; V Rider; N I Abdou; B Kimler
Journal:  Lupus       Date:  2013-03-27       Impact factor: 2.911

9.  NR2F1 mutations cause optic atrophy with intellectual disability.

Authors:  Daniëlle G M Bosch; F Nienke Boonstra; Claudia Gonzaga-Jauregui; Mafei Xu; Joep de Ligt; Shalini Jhangiani; Wojciech Wiszniewski; Donna M Muzny; Helger G Yntema; Rolph Pfundt; Lisenka E L M Vissers; Liesbeth Spruijt; Ellen A W Blokland; Chun-An Chen; Richard A Lewis; Sophia Y Tsai; Richard A Gibbs; Ming-Jer Tsai; James R Lupski; Huda Y Zoghbi; Frans P M Cremers; Bert B A de Vries; Christian P Schaaf
Journal:  Am J Hum Genet       Date:  2014-01-23       Impact factor: 11.025

Review 10.  Minireview: role of orphan nuclear receptors in cancer and potential as drug targets.

Authors:  Stephen Safe; Un-Ho Jin; Erik Hedrick; Alexandra Reeder; Syng-Ook Lee
Journal:  Mol Endocrinol       Date:  2013-12-02
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