| Literature DB >> 21256438 |
Igor E Brodsky1, Ruslan Medzhitov.
Abstract
Caspase-1 plays a key role in host defense through its dual function in inducing a pro-inflammatory cell death termed pyroptosis and in promoting the secretion of pro-inflammatory cytokines. A new study now highlights the specific importance of pyroptosis in resistance to intracellular pathogens. Copyright ÂEntities:
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Year: 2011 PMID: 21256438 DOI: 10.1016/j.cub.2010.12.008
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834