Literature DB >> 21256242

Putting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) production.

Kathryn H Richards1, Andrew Macdonald.   

Abstract

Type I IFNs (IFNα/β) are essential anti-viral cytokines produced in response to the detection of viral components by host pattern recognition receptors. IFNα/β production is transient, and aberrant activation can be hazardous to the host. In this article, we review our current understanding of host negative regulatory mechanisms that control IFNα/β production.
Copyright © 2011 Institut Pasteur. Published by Elsevier SAS. All rights reserved.

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Year:  2011        PMID： 21256242     DOI： 10.1016/j.micinf.2010.12.007

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  27 in total

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2.  Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells.

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5.  Poly(C)-binding protein 1 (PCBP1) mediates housekeeping degradation of mitochondrial antiviral signaling (MAVS).

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Journal:  J Virol       Date:  2019-03-21       Impact factor: 5.103

8.  LYAR Suppresses Beta Interferon Induction by Targeting Phosphorylated Interferon Regulatory Factor 3.

Authors:  Cha Yang; Xiaokun Liu; Tailang Cheng; Rong Xiao; Qingxia Gao; Fan Ming; Meilin Jin; Huanchun Chen; Hongbo Zhou
Journal:  J Virol       Date:  2019-10-15       Impact factor: 5.103

9.  Strand-Specific Dual RNA Sequencing of Bronchial Epithelial Cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions.

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10.  Viral infection dampens human fetal membrane type I interferon responses triggered by bacterial LPS.

Authors:  Julie A Potter; Mancy Tong; Paulomi Aldo; Ja Young Kwon; Mary Pitruzzello; Gil Mor; Vikki M Abrahams
Journal:  J Reprod Immunol       Date:  2020-04-08       Impact factor: 4.054
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