Literature DB >> 21254565

[Comparative analysis of the DXPas34 regulatory region in rodents].

A A Malakhova, M S Piatkova, E A Elisafenko, A I Shevchenko, A É Kel', S M Zakiian.   

Abstract

Mouse X chromosome inactivation center contains the DXPas34 minisatellite locus which plays an important role in expression regulation of the Tsix and Xist genes, involved into female dosage compensation. Comparative analysis of the DXPas34 locus from mouse, rat, and four common vole species revealed similar organization of this region in the form of tandem repeat blocks. A search for functionally important elements in this locus showed that all the species examined carried the conservative motif monomers, which could be involved in regulation of X inactivation.

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Year:  2010        PMID: 21254565

Source DB:  PubMed          Journal:  Genetika        ISSN: 0016-6758


  1 in total

1.  Expression of endogenous retroviruses is negatively regulated by the pluripotency marker Rex1/Zfp42.

Authors:  D Guallar; R Pérez-Palacios; M Climent; I Martínez-Abadía; A Larraga; M Fernández-Juan; C Vallejo; P Muniesa; J Schoorlemmer
Journal:  Nucleic Acids Res       Date:  2012-07-25       Impact factor: 16.971

  1 in total

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