Literature DB >> 21253772

Is testicular germ cell cancer associated with increased muscle mass or adiposity?

Manuel Gmeiner1, Stephan Hruby, Andreas Nachbagauer, Wolfgang Krampla.   

Abstract

INTRODUCTION: The correlation between an increased body mass index and testicular germ cell cancer has been a topical subject matter of literature. The thesis examines whether for patients with germ cell cancer of the testis the relation between the body cross section and the muscle mass at a particular spot at the abdomen is dislocated toward muscle hypertrophy. PATIENTS, MATERIALS, AND METHODS: CT examinations of 120 patients with testicular tumor have been compared to CTs of 60 trauma surgery patients. MEASUREMENTS: In thickness of the layer at the lowest point of the umbilicus the area of the total body cross section and the Mm. psoas majores were determined and their quotient was calculated. Furthermore, the thickness of the M. rectus abdominis and the Mm. obliquii abdominis have been determined at the broadest spot.
RESULTS: The reproducibility of the measured data has been extremely high (kappa >0.9). There has been no significant difference in any of the examined parameters between the comparison group and the total patient group. DISCUSSION: According to the literature, patients with germ cell cancer of the testis on average show a higher body-mass-index (BMI) compared to a comparable group of equivalent age. The height of the umbilicus is a body region, where for adipose humans the amplitude increases markedly, hence for reference measurement appropriate. On the basis of the outcome of this thesis, the most probable explanation for the BMI rise is weight gain at other body parts.

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Year:  2011        PMID: 21253772     DOI: 10.1007/s00508-010-1525-8

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  11 in total

1.  Sonographic subcutaneous and visceral fat indices represent the distribution of body fat volume.

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2.  Is risk of testicular cancer related to body size?

Authors:  Klaus-Peter Dieckmann; Uwe Pichlmeier
Journal:  Eur Urol       Date:  2002-12       Impact factor: 20.096

3.  Blood pressure and body mass index in long-term survivors of testicular cancer.

Authors:  H Sagstuen; N Aass; S D Fosså; O Dahl; O Klepp; E A Wist; T Wilsgaard; R M Bremnes
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4.  The impact of height and body mass index on the risk of testicular cancer in 600,000 Norwegian men.

Authors:  Tone Bjørge; Steinar Tretli; A Kathrine Lie; Anders Engeland
Journal:  Cancer Causes Control       Date:  2006-09       Impact factor: 2.506

5.  Protein-calorie malnutrition associated with alcoholic hepatitis. Veterans Administration Cooperative Study Group on Alcoholic Hepatitis.

Authors:  C L Mendenhall; S Anderson; R E Weesner; S J Goldberg; K A Crolic
Journal:  Am J Med       Date:  1984-02       Impact factor: 4.965

Review 6.  Gynaecomastia: an endocrine manifestation of testicular cancer.

Authors:  H C Hassan; I M Cullen; R G Casey; E Rogers
Journal:  Andrologia       Date:  2008-06       Impact factor: 2.775

7.  Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase.

Authors:  Lutz Philipp Breitling; Elke Raum; Heiko Müller; Dietrich Rothenbacher; Hermann Brenner
Journal:  Hepatology       Date:  2009-03       Impact factor: 17.425

8.  Testicular tumours presenting as gynaecomastia.

Authors:  I R Daniels; G T Layer
Journal:  Eur J Surg Oncol       Date:  2003-06       Impact factor: 4.424

9.  Is increased body mass index associated with the incidence of testicular germ cell cancer?

Authors:  Klaus-Peter Dieckmann; Jörg Thomas Hartmann; Johannes Classen; Malte Diederichs; Uwe Pichlmeier
Journal:  J Cancer Res Clin Oncol       Date:  2008-11-11       Impact factor: 4.553

10.  Tallness is associated with risk of testicular cancer: evidence for the nutrition hypothesis.

Authors:  K-P Dieckmann; J T Hartmann; J Classen; R Lüdde; M Diederichs; U Pichlmeier
Journal:  Br J Cancer       Date:  2008-09-30       Impact factor: 7.640

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