| Literature DB >> 21253743 |
Abstract
Biologics are increasingly being used in the treatment of non-infectious sight-threatening uveitis. While the advantages of biologics, such as avoidance of glucocorticoid side-effects or rapid control of intraocular inflammation therapy refractive to corticosteroids, cannot be dismissed the treating ophthalmologist should be aware of the specific risks. Biologics increase the risk for severe and atypical infections, lymphomas and other malignancies. Treatment should only be initiated when profound knowledge about indications, management and monitoring of treatment with biologics is readily available. Weighing up the risks versus the benefits should be made on an individual basis and guide patient consultation.Entities:
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Year: 2011 PMID: 21253743 DOI: 10.1007/s00347-010-2257-x
Source DB: PubMed Journal: Ophthalmologe ISSN: 0941-293X Impact factor: 1.059