BACKGROUND/AIMS: Several studies have found that the frequency of colorectal polyps increases significantly from the age of 50 years. The goal of this study was to determine the differences in the clinical characteristics of colorectal polyps between patients aged 50 years and older, and younger patients. METHODS: The colonoscopy database of 3,304 patients at the Yeungnam University Medical Center between January 2009 and December 2009 was reviewed retrospectively. In total, 679 patients were divided into the younger group (n=170) and the older group (aged ≥50 years) (n=509). A matched case-control study was performed using propensity scores and 117 patients selected from each group. RESULTS: Compared to the younger group, the older group had a significantly higher proportion of female patients, and patients with hypertension, a smoking history, and a history of taking medications. After performing the matched case-control study, 234 patients and 679 colon polyps were included in the analysis. Compared to the younger patients, the older patients had a significantly higher proportion of multiple lesions (57.3% vs 25.6%, p<0.001), left- and right-side distribution (35.9% vs 12.0%, p<0.001), and larger polyps (mean 9.1 mm vs 6.3 mm, p<0.001). A left-sided distribution was less common in the older group than in the younger group (35.0% vs 51.3%, p=0.025). CONCLUSIONS: The methods used to screen for colorectal cancer in older patients should include colonoscopy due to the shift to the right side as a common location for colorectal polyps in that age group.
BACKGROUND/AIMS: Several studies have found that the frequency of colorectal polyps increases significantly from the age of 50 years. The goal of this study was to determine the differences in the clinical characteristics of colorectal polyps between patients aged 50 years and older, and younger patients. METHODS: The colonoscopy database of 3,304 patients at the Yeungnam University Medical Center between January 2009 and December 2009 was reviewed retrospectively. In total, 679 patients were divided into the younger group (n=170) and the older group (aged ≥50 years) (n=509). A matched case-control study was performed using propensity scores and 117 patients selected from each group. RESULTS: Compared to the younger group, the older group had a significantly higher proportion of female patients, and patients with hypertension, a smoking history, and a history of taking medications. After performing the matched case-control study, 234 patients and 679 colon polyps were included in the analysis. Compared to the younger patients, the older patients had a significantly higher proportion of multiple lesions (57.3% vs 25.6%, p<0.001), left- and right-side distribution (35.9% vs 12.0%, p<0.001), and larger polyps (mean 9.1 mm vs 6.3 mm, p<0.001). A left-sided distribution was less common in the older group than in the younger group (35.0% vs 51.3%, p=0.025). CONCLUSIONS: The methods used to screen for colorectal cancer in older patients should include colonoscopy due to the shift to the right side as a common location for colorectal polyps in that age group.
Authors: Hassan Ashktorab; Duane T Smoot; Haleh Farzanmehr; Marie Fidelia-Lambert; Bahram Momen; Linda Hylind; Christine Iacosozio-Dononue; John M Carethers; Ajay Goel; C Richard Boland; Francis M Giardiello Journal: Int J Cancer Date: 2005-10-10 Impact factor: 7.396
Authors: Christine Hachem; Robert Morgan; Michael Johnson; Mark Kuebeler; Hashem El-Serag Journal: Am J Gastroenterol Date: 2009-04-07 Impact factor: 10.864
Authors: J D Potter; J Bigler; L Fosdick; R M Bostick; E Kampman; C Chen; T A Louis; P Grambsch Journal: Cancer Epidemiol Biomarkers Prev Date: 1999-01 Impact factor: 4.254
Authors: Hee Sun Kim; Su Jung Baik; Kyung Hee Kim; Cho Rong Oh; Jung Hyun Lee; Wan Jae Jo; Hye Kyoung Kim; Eun Young Kim; Min Jung Kim Journal: Gut Liver Date: 2013-06-11 Impact factor: 4.519