Julie J Keysor1, Alana Brembs. 1. Department of Physical Therapy and Athletic Training, College of Health and Rehabilitation Sciences: Sargent and Clinical Epidemiology Research and Training Unit, Boston University, Boston, Massachusetts 02215, USA. jkeysor@bu.edu
Abstract
PURPOSE OF REVIEW: Several recent clinical trials and systematic reviews have examined functional outcomes of exercise programs in two populations: older adults and adults with knee arthritis. We synthesize recent clinical trials and systematic reviews to examine whether the links between exercise and functional outcomes are better understood than they were a decade ago. RECENT FINDINGS: Systematic reviews and current clinical trials reveal a modest beneficial effect of progressive resistance training (strengthening programs) and aerobic programs on strength, pain, and function in both populations. Few randomized controlled trials have investigated disability-level outcomes, and of those that do examine disability outcomes, the majority of studies have not shown a beneficial effect. SUMMARY: Current and recent evidence shows little to no impact of exercise on the prevention of disability. Exercise programs may need to be changed if the desire is to prevent or minimize disability. Alternatively, different strategies need to be developed to address disability more directly.
PURPOSE OF REVIEW: Several recent clinical trials and systematic reviews have examined functional outcomes of exercise programs in two populations: older adults and adults with knee arthritis. We synthesize recent clinical trials and systematic reviews to examine whether the links between exercise and functional outcomes are better understood than they were a decade ago. RECENT FINDINGS: Systematic reviews and current clinical trials reveal a modest beneficial effect of progressive resistance training (strengthening programs) and aerobic programs on strength, pain, and function in both populations. Few randomized controlled trials have investigated disability-level outcomes, and of those that do examine disability outcomes, the majority of studies have not shown a beneficial effect. SUMMARY: Current and recent evidence shows little to no impact of exercise on the prevention of disability. Exercise programs may need to be changed if the desire is to prevent or minimize disability. Alternatively, different strategies need to be developed to address disability more directly.
Authors: Stephen D Anton; Adam J Woods; Tetso Ashizawa; Diana Barb; Thomas W Buford; Christy S Carter; David J Clark; Ronald A Cohen; Duane B Corbett; Yenisel Cruz-Almeida; Vonetta Dotson; Natalie Ebner; Philip A Efron; Roger B Fillingim; Thomas C Foster; David M Gundermann; Anna-Maria Joseph; Christy Karabetian; Christiaan Leeuwenburgh; Todd M Manini; Michael Marsiske; Robert T Mankowski; Heather L Mutchie; Michael G Perri; Sanjay Ranka; Parisa Rashidi; Bhanuprasad Sandesara; Philip J Scarpace; Kimberly T Sibille; Laurence M Solberg; Shinichi Someya; Connie Uphold; Stephanie Wohlgemuth; Samuel Shangwu Wu; Marco Pahor Journal: Ageing Res Rev Date: 2015-10-14 Impact factor: 10.895
Authors: Marla K Beauchamp; Jonathan F Bean; Rachel E Ward; Laura A Kurlinski; Nancy K Latham; Alan M Jette Journal: J Am Geriatr Soc Date: 2015-06-01 Impact factor: 5.562
Authors: Jennifer S Brach; Subashan Perera; Sandra Gilmore; Jessie M VanSwearingen; Deborah Brodine; David Wert; Neelesh K Nadkarni; Edmund Ricci Journal: Contemp Clin Trials Date: 2016-08-10 Impact factor: 2.226
Authors: Jennifer S Brach; Sara J Francois; Jessie M VanSwearingen; Sandra Gilmore; Subashan Perera; Stephanie A Studenski Journal: PM R Date: 2015-10-19 Impact factor: 2.298
Authors: Andrew S Layne; Fang-Chi Hsu; Steven N Blair; Shyh-Huei Chen; Jennifer Dungan; Roger A Fielding; Nancy W Glynn; Alexandra M Hajduk; Abby C King; Todd M Manini; Anthony P Marsh; Marco Pahor; Christine A Pellegrini; Thomas W Buford Journal: Arch Phys Med Rehabil Date: 2016-08-25 Impact factor: 3.966
Authors: Marla K Beauchamp; Alan M Jette; Pengsheng Ni; Nancy K Latham; Rachel E Ward; Laura A Kurlinski; Sanja Percac-Lima; Suzanne G Leveille; Jonathan F Bean Journal: J Gerontol A Biol Sci Med Sci Date: 2015-09-13 Impact factor: 6.053
Authors: Sara A Harper; John R Bassler; Sujitha Peramsetty; Youfeng Yang; Lisa M Roberts; Devin Drummer; Robert T Mankowski; Christiaan Leeuwenburgh; Karina Ricart; Rakesh P Patel; Marcas M Bamman; Stephen D Anton; Byron C Jaeger; Thomas W Buford Journal: Exp Gerontol Date: 2020-10-15 Impact factor: 4.032