BACKGROUND: To describe the design of the baseline assessment of an epidemiological study of elderly persons living in Salamanca, central-western Spain: the Neurological Diseases in Salamanca (NEDISA) study. We assessed the epidemiology of stroke, cognitive disorders, essential tremor (ET), Parkinson's disease (PD) and restless legs syndrome. METHODS: In phase 1 (February 1 to May 31, 2007), 4 neurologists and 2 trained general physicians examined and performed phlebotomy on all participants. In phase 2 (June 1, 2007, to June 1, 2008), the participants were reexamined and had a complete neuropsychological assessment. Neuroimaging was performed in participants with cognitive disorders, ET and PD. RESULTS: The registered study population consisted of 1,077 individuals, but 45 people were ineligible (address change, refusals or death), leaving a final sample of 1,032 (95.8%). The main demographic data on the 1,032 participants (408 men, 624 women) are provided. CONCLUSIONS: Most of the registered study population was enrolled, and this may have been due to the close relationship between NEDISA researchers and the general physicians in the area of study. The NEDISA study will likely improve our knowledge of prevalence rates of the neurological diseases chosen for study as well as the set of risk factors that predispose individuals in Spain to these disorders.
BACKGROUND: To describe the design of the baseline assessment of an epidemiological study of elderly persons living in Salamanca, central-western Spain: the Neurological Diseases in Salamanca (NEDISA) study. We assessed the epidemiology of stroke, cognitive disorders, essential tremor (ET), Parkinson's disease (PD) and restless legs syndrome. METHODS: In phase 1 (February 1 to May 31, 2007), 4 neurologists and 2 trained general physicians examined and performed phlebotomy on all participants. In phase 2 (June 1, 2007, to June 1, 2008), the participants were reexamined and had a complete neuropsychological assessment. Neuroimaging was performed in participants with cognitive disorders, ET and PD. RESULTS: The registered study population consisted of 1,077 individuals, but 45 people were ineligible (address change, refusals or death), leaving a final sample of 1,032 (95.8%). The main demographic data on the 1,032 participants (408 men, 624 women) are provided. CONCLUSIONS: Most of the registered study population was enrolled, and this may have been due to the close relationship between NEDISA researchers and the general physicians in the area of study. The NEDISA study will likely improve our knowledge of prevalence rates of the neurological diseases chosen for study as well as the set of risk factors that predispose individuals in Spain to these disorders.
Authors: R Blesa; M Pujol; M Aguilar; P Santacruz; I Bertran-Serra; G Hernández; J M Sol; J Peña-Casanova Journal: Neuropsychologia Date: 2001 Impact factor: 3.139
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Authors: H Feldman; A Sauter; A Donald; I Gélinas; S Gauthier; K Torfs; W Parys; A Mehnert Journal: Alzheimer Dis Assoc Disord Date: 2001 Apr-Jun Impact factor: 2.703
Authors: Richard P Allen; Daniel Picchietti; Wayne A Hening; Claudia Trenkwalder; Arthur S Walters; Jacques Montplaisi Journal: Sleep Med Date: 2003-03 Impact factor: 3.492
Authors: Miguel Angel Tola-Arribas; María José Garea; María Isabel Yugueros; Fernando Ortega-Valín; Ana Cerón; Beatriz Fernández-Malvido; Marta González-Touya; Antonio San José; Ana Botrán; Vanessa Iglesias; Bárbara Díaz-Gómez Journal: BMC Neurol Date: 2012-08-30 Impact factor: 2.474
Authors: Victoria Castrillo-Fraile; Elena Casas Peña; José María Trejo Gabriel Y Galán; Pedro David Delgado-López; Carla Collazo; Esther Cubo Journal: Tremor Other Hyperkinet Mov (N Y) Date: 2019-12-05