Literature DB >> 21251610

Metastatic colon cancer cells negotiate the intravasation Notch.

Gerhard Christofori1.   

Abstract

In this issue of Cancer Cell, Sonoshita et al. report that Aes/Grg5 prevents metastasis of colorectal cancer cells by sequestering and inactivating Notch transcriptional effectors in distinct nuclear foci. Loss of Aes/Grg5 in invasive cancer cells where Notch is activated by stroma-expressed ligands promotes invasion, transendothelial migration, intravasation, and metastasis. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21251610     DOI： 10.1016/j.ccr.2011.01.003

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  6 in total

Review 1.  Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation.

Authors:  Teodora Ribarska; Klaus-Marius Bastian; Annemarie Koch; Wolfgang A Schulz
Journal:  Asian J Androl       Date:  2012-02-27       Impact factor: 3.285

2.  Notch: architect, landscaper, and guardian of the intestine.

Authors:  Marc Vooijs; Zhenyi Liu; Raphael Kopan
Journal:  Gastroenterology       Date:  2011-06-12       Impact factor: 22.682

3.  Common and complex Notch1 mutations in Chinese oral squamous cell carcinoma.

Authors:  Xiaomeng Song; Ronghui Xia; Jiang Li; Zhifeng Long; Hening Ren; Wantao Chen; Li Mao
Journal:  Clin Cancer Res       Date:  2013-11-25       Impact factor: 12.531

4.  Notch-mediated induction of N-cadherin and α9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells.

Authors:  A Masià; A Almazán-Moga; P Velasco; J Reventós; N Torán; J Sánchez de Toledo; J Roma; S Gallego
Journal:  Br J Cancer       Date:  2012-09-13       Impact factor: 7.640

5.  Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling.

Authors:  Pingli Mo; Qiling Zhou; Lei Guan; Yi Wang; Wei Wang; Mengmeng Miao; Zhangwei Tong; Ming Li; Sidra Majaz; Yonghong Liu; Guoqiang Su; Jianming Xu; Chundong Yu
Journal:  Oncogene       Date:  2014-09-29       Impact factor: 9.867

6.  Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas.

Authors:  Jian Liu; Huijie Fan; Yuanyuan Ma; Dongming Liang; Ruixia Huang; Junsheng Wang; Fuyou Zhou; Quancheng Kan; Liang Ming; Huixiang Li; Karl-Erik Giercksky; Jahn Martin Nesland; Zhenhe Suo
Journal:  PLoS One       Date:  2013-02-07       Impact factor: 3.240
  6 in total

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