Literature DB >> 21249496

Massive localised lymphoedema: clinical presentation and MR imaging characteristics.

Monica Khanna1, Ali M Naraghi, David Salonen, Rejpaul Bhumbra, Brendan C Dickson, Mark J Kransdorf, Lawrence M White.   

Abstract

Three morbidly obese women were referred to us with suspected soft-tissue sarcomas. All lesions arose from the medial subcutaneous tissues of the thigh, and were shown to represent massive localised lymphoedema (MLL), a rare condition occurring in morbidly obese adults. MR imaging typically demonstrates a sharply demarcated, pedunculated mass consisting of fat partitioned by fibrous septae surrounded by a thickened dermis. There is oedema both within the mass and tracking along the subcutaneous septae in a "lace-like" fashion outwards from the pedicle, outlining large lobules of fat. Minimal enhancement is observed within the dermis of the lesion following intravenous gadolinium administration. Obesity is a growing problem that is likely to result in an increase in the prevalence of this condition; therefore, familiarity with the radiological appearance is important in establishing a correct diagnosis in this condition that may mimic a soft-tissue sarcoma.

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Year:  2011        PMID: 21249496     DOI: 10.1007/s00256-010-1080-4

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  4 in total

1.  Massive localized lymphedema of the thigh in a morbidly obese patient.

Authors:  M Berenji; A Kalani; J Kim; K Kelly; M K Wallack
Journal:  Eur J Surg Oncol       Date:  2009-05-28       Impact factor: 4.424

2.  Massive localized lymphedema: additional locations and association with hypothyroidism.

Authors:  D Wu; J Gibbs; D Corral; M Intengan; J J Brooks
Journal:  Hum Pathol       Date:  2000-09       Impact factor: 3.466

Review 3.  Massive localised lymphoedema: a clinicopathological study of 22 cases and review of the literature.

Authors:  M Manduch; A M Oliveira; A G Nascimento; A L Folpe
Journal:  J Clin Pathol       Date:  2009-09       Impact factor: 3.411

Review 4.  Massive localized lymphedema in the morbidly obese: a histologically distinct reactive lesion simulating liposarcoma.

Authors:  G Farshid; S W Weiss
Journal:  Am J Surg Pathol       Date:  1998-10       Impact factor: 6.394

  4 in total
  4 in total

1.  Imaging findings of adiposis dolorosa vs. massive localized lymphedema.

Authors:  Jonelle M Petscavage-Thomas; Eric A Walker; Stephanie A Bernard; Jennifer Bennett
Journal:  Skeletal Radiol       Date:  2015-02-13       Impact factor: 2.199

2.  Angiosarcoma arising in massive localized lymphedema.

Authors:  Samantha Dyroff; Lester J Layfield; Julia Crim
Journal:  Skeletal Radiol       Date:  2020-01-16       Impact factor: 2.199

3.  Massive localized lymphedema: a clinicopathologic study of 46 patients with an enrichment for multiplicity.

Authors:  Habibe Kurt; Christina A Arnold; Jason E Payne; Michael J Miller; Roman J Skoracki; O Hans Iwenofu
Journal:  Mod Pathol       Date:  2015-11-20       Impact factor: 7.842

4.  Massive localized lymphedema of the thigh mimicking liposarcoma.

Authors:  Jack Porrino; Josh Walsh
Journal:  Radiol Case Rep       Date:  2016-09-17
  4 in total

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