Literature DB >> 21249061

Does Antihypertensive Therapy Need to be Life-Long?

J Lemelin.   

Abstract

The author reviews the evidence for and against decreasing or discontinuing antihypertensive therapy on known hypertensive patients once their blood pressure has been brought under control. The evidence supports a trial of decreasing and, in many cases, discontinuing antihypertensive medication. Although there are no established protocols for cessation of therapy, the author discusses suggestions in the literature.

Entities:  

Year:  1989        PMID： 21249061      PMCID： PMC2280900     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  7 in total

Review 1.  Considerations in the long-term treatment of hypertension.

Authors:  R M Graham
Journal:  Clin Ther       Date:  1983       Impact factor: 3.393

2.  Step-down therapy for hypertension. Results of withdrawal from multiple drugs and from a single drug.

Authors:  F A Finnerty
Journal:  Postgrad Med       Date:  1985-05-15       Impact factor: 3.840

3.  Persistence of normal BP after withdrawal of drug treatment in mild hypertension.

Authors:  P D Levinson; I M Khatri; E D Freis
Journal:  Arch Intern Med       Date:  1982-12

4.  Step-down treatment of mild systemic hypertension.

Authors:  F A Finnerty
Journal:  Am J Cardiol       Date:  1984-05-01       Impact factor: 2.778

5.  Step-down therapy for hypertension. Results in a community-based program.

Authors:  M H Alderman; T K Davis; L M Gerber
Journal:  Postgrad Med       Date:  1985-05-15       Impact factor: 3.840

6.  Dietary therapy slows the return of hypertension after stopping prolonged medication.

Authors:  H G Langford; M D Blaufox; A Oberman; C M Hawkins; J D Curb; G R Cutter; S Wassertheil-Smoller; S Pressel; C Babcock; J D Abernethy
Journal:  JAMA       Date:  1985-02-01       Impact factor: 56.272

7.  Separation of essential hypertensive patients based on blood pressure responses after the withdrawal of antihypertensive agents by step-wise discriminant analysis.

Authors:  P G Fernandez; B K Kim; A B Galway; J N Sharma
Journal:  Curr Med Res Opin       Date:  1983       Impact factor: 2.580
  7 in total

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