Literature DB >> 21248691

Facilitating the analysis of immunological data with visual analytic techniques.

David C Shih1, Kevin C Ho, Kyle M Melnick, Ronald A Rensink, Tobias R Kollmann, Edgardo S Fortuno.   

Abstract

Visual analytics (VA) has emerged as a new way to analyze large dataset through interactive visual display. We demonstrated the utility and the flexibility of a VA approach in the analysis of biological datasets. Examples of these datasets in immunology include flow cytometry, Luminex data, and genotyping (e.g., single nucleotide polymorphism) data. Contrary to the traditional information visualization approach, VA restores the analysis power in the hands of analyst by allowing the analyst to engage in real-time data exploration process. We selected the VA software called Tableau after evaluating several VA tools. Two types of analysis tasks analysis within and between datasets were demonstrated in the video presentation using an approach called paired analysis. Paired analysis, as defined in VA, is an analysis approach in which a VA tool expert works side-by-side with a domain expert during the analysis. The domain expert is the one who understands the significance of the data, and asks the questions that the collected data might address. The tool expert then creates visualizations to help find patterns in the data that might answer these questions. The short lag-time between the hypothesis generation and the rapid visual display of the data is the main advantage of a VA approach.

Mesh:

Year:  2011        PMID: 21248691      PMCID: PMC3182632          DOI: 10.3791/2397

Source DB:  PubMed          Journal:  J Vis Exp        ISSN: 1940-087X            Impact factor:   1.355


  2 in total

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Authors:  Purvi Saraiya; Chris North; Vy Lam; Karen A Duca
Journal:  IEEE Trans Vis Comput Graph       Date:  2006 Nov-Dec       Impact factor: 4.579

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Authors:  Tobias R Kollmann; Juliet Crabtree; Annie Rein-Weston; Darren Blimkie; Francis Thommai; Xiu Yu Wang; Pascal M Lavoie; Jeff Furlong; Edgardo S Fortuno; Adeline M Hajjar; Natalie R Hawkins; Steven G Self; Christopher B Wilson
Journal:  J Immunol       Date:  2009-11-16       Impact factor: 5.422

  2 in total
  5 in total

1.  Cytotoxicity patterns of arsenic trioxide exposure on HaCaT keratinocytes.

Authors:  Udensi K Udensi; Barbara E Graham-Evans; Christian Rogers; Raphael D Isokpehi
Journal:  Clin Cosmet Investig Dermatol       Date:  2011-12-09

2.  Functional Annotation Analytics of Rhodopseudomonas palustris Genomes.

Authors:  Shaneka S Simmons; Raphael D Isokpehi; Shyretha D Brown; Donee L McAllister; Charnia C Hall; Wanaki M McDuffy; Tamara L Medley; Udensi K Udensi; Rajendram V Rajnarayanan; Wellington K Ayensu; Hari H P Cohly
Journal:  Bioinform Biol Insights       Date:  2011-09-21

3.  Real-Time Enrollment Dashboard For Multisite Clinical Trials.

Authors:  William A Mattingly; Robert R Kelley; Timothy L Wiemken; Julia H Chariker; Paula Peyrani; Brian E Guinn; Laura E Binford; Kimberley Buckner; Julio Ramirez
Journal:  Contemp Clin Trials Commun       Date:  2015-10-30

4.  Pattern recognition receptor-mediated cytokine response in infants across 4 continents.

Authors:  Kinga K Smolen; Candice E Ruck; Edgardo S Fortuno; Kevin Ho; Pedro Dimitriu; William W Mohn; David P Speert; Philip J Cooper; Monika Esser; Tessa Goetghebuer; Arnaud Marchant; Tobias R Kollmann
Journal:  J Allergy Clin Immunol       Date:  2013-11-28       Impact factor: 10.793

5.  Clinical laboratory analytics: Challenges and promise for an emerging discipline.

Authors:  Brian H Shirts; Brian R Jackson; Geoffrey S Baird; Jason M Baron; Bryan Clements; Ricky Grisson; Ronald George Hauser; Julie R Taylor; Enrique Terrazas; Brad Brimhall
Journal:  J Pathol Inform       Date:  2015-02-24
  5 in total

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