Literature DB >> 21247153

Identification and characterization of the first ovothiol biosynthetic enzyme.

Andrea Braunshausen1, Florian P Seebeck.   

Abstract

Ovothiols are histidine-derived thiols that were first isolated from marine invertebrates. We have identified a 5-histidylcysteine sulfoxide synthase (OvoA) as the first ovothiol biosynthetic enzyme and characterized OvoAs from Erwinia tasmaniensis and Trypanosoma cruzi . Homologous enzymes are encoded in more than 80 genomes ranging from proteobacteria to animalia.

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Year:  2011        PMID： 21247153     DOI： 10.1021/ja109378e

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  37 in total

1.  Regioselectivity of the oxidative C-S bond formation in ergothioneine and ovothiol biosyntheses.

Authors:  Heng Song; Maureen Leninger; Norman Lee; Pinghua Liu
Journal:  Org Lett       Date:  2013-09-09       Impact factor: 6.005

Review 2.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors:  Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal:  Chem Rev       Date:  2017-04-04       Impact factor: 60.622

3.  The complex evolutionary history of sulfoxide synthase in ovothiol biosynthesis.

Authors:  Marco Gerdol; Marco Sollitto; Alberto Pallavicini; Immacolata Castellano
Journal:  Proc Biol Sci       Date:  2019-11-27       Impact factor: 5.349

4.  Crystal Structure of the Ergothioneine Sulfoxide Synthase from Candidatus Chloracidobacterium thermophilum and Structure-Guided Engineering To Modulate Its Substrate Selectivity.

Authors:  Nathchar Naowarojna; Seema Irani; Weiyao Hu; Ronghai Cheng; Li Zhang; Xinhao Li; Jiesheng Chen; Yan Jessie Zhang; Pinghua Liu
Journal:  ACS Catal       Date:  2019-07-02       Impact factor: 13.084

Review 5.  The biosynthetic diversity of the animal world.

Authors:  Joshua P Torres; Eric W Schmidt
Journal:  J Biol Chem       Date:  2019-10-11       Impact factor: 5.157

6.  Minimum set of cytochromes P450 for reconstituting the biosynthesis of camalexin, a major Arabidopsis antibiotic.

Authors:  Andrew P Klein; Gülbenk Anarat-Cappillino; Elizabeth S Sattely
Journal:  Angew Chem Int Ed Engl       Date:  2013-10-21       Impact factor: 15.336

Review 7.  Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes.

Authors:  Spencer C Peck; Wilfred A van der Donk
Journal:  J Biol Inorg Chem       Date:  2016-10-25       Impact factor: 3.358

8.  Use of a Tyrosine Analogue To Modulate the Two Activities of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis, Cysteine Oxidation versus Oxidative C-S Bond Formation.

Authors:  Li Chen; Nathchar Naowarojna; Heng Song; Shu Wang; Jiangyun Wang; Zixin Deng; Changming Zhao; Pinghua Liu
Journal:  J Am Chem Soc       Date:  2018-03-21       Impact factor: 15.419

9.  Sulfur-containing histidine compounds inhibit γ-glutamyl transpeptidase activity in human cancer cells.

Authors:  Mariarita Brancaccio; Maria Russo; Mariorosario Masullo; Anna Palumbo; Gian Luigi Russo; Immacolata Castellano
Journal:  J Biol Chem       Date:  2019-08-02       Impact factor: 5.157

Review 10.  Mini-Review: Ergothioneine and Ovothiol Biosyntheses, an Unprecedented Trans-Sulfur Strategy in Natural Product Biosynthesis.

Authors:  Nathchar Naowarojna; Ronghai Cheng; Li Chen; Melissa Quill; Meiling Xu; Changming Zhao; Pinghua Liu
Journal:  Biochemistry       Date:  2018-04-06       Impact factor: 3.162
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