Literature DB >> 21245751

Should all ischemic mitral regurgitation be repaired? When should we replace?

Damien J LaPar1, Irving L Kron.   

Abstract

PURPOSE OF REVIEW: Ischemic mitral regurgitation (IMR) is a major source of morbidity and mortality. Although mitral valve repair has become recently popularized for the treatment of IMR, select patients may derive benefits from replacement. The purpose of this review is to describe current surgical options for IMR and to discuss when mitral valve replacement (MVR) may be favored over mitral valve repair. RECENT
FINDINGS: Current surgical options for the treatment of IMR include surgical revascularization alone, mitral valve repair, or MVR. Although surgical revascularization alone may benefit patients with mild-moderate IMR, most surgeons advocate the performance of revascularization in combination with either mitral valve repair or replacement. In the current era, mitral valve repair has proven to offer improved short-term and long-term survival, decreased valve-related morbidity, and improved left ventricular function compared with MVR. However, MVR should be considered for high-risk patients and those with specific underlying mechanisms of IMR.
SUMMARY: In the absence of level one evidence, mitral valve repair offers an effective and durable surgical approach to the treatment of mitral insufficiency and remains the operation of choice for IMR. MVR, however, is preferred for select patients. Future randomized, prospective clinical trials are needed to directly compare these surgical techniques.

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Year:  2011        PMID: 21245751      PMCID: PMC3071620          DOI: 10.1097/HCO.0b013e3283439888

Source DB:  PubMed          Journal:  Curr Opin Cardiol        ISSN: 0268-4705            Impact factor:   2.161


  44 in total

1.  Ischemic mitral regurgitation redux--to repair or to replace?

Authors:  D C Miller
Journal:  J Thorac Cardiovasc Surg       Date:  2001-12       Impact factor: 5.209

2.  The importance of grade 2 ischemic mitral regurgitation in coronary artery bypass grafting.

Authors:  T Rydén; O Bech-Hanssen; G Brandrup-Wognsen; F Nilsson; S Svensson; A Jeppsson
Journal:  Eur J Cardiothorac Surg       Date:  2001-08       Impact factor: 4.191

3.  Mitral repair is superior to replacement when associated with coronary artery disease.

Authors:  T Brett Reece; Curtis G Tribble; Peter I Ellman; Thomas S Maxey; Randall L Woodford; George M Dimeling; Harry A Wellons; Ivan K Crosby; John A Kern; Irving L Kron
Journal:  Ann Surg       Date:  2004-05       Impact factor: 12.969

Review 4.  Surgical treatment of the ischemic mitral valve.

Authors:  David H Adams; Farzan Filsoufi; Lishan Aklog
Journal:  J Heart Valve Dis       Date:  2002-01

5.  Ischemic mitral valve reconstruction and replacement: comparison of long-term survival and complications.

Authors:  E A Grossi; J D Goldberg; A LaPietra; X Ye; P Zakow; M Sussman; J Delianides; A T Culliford; R A Esposito; G H Ribakove; A C Galloway; S B Colvin
Journal:  J Thorac Cardiovasc Surg       Date:  2001-12       Impact factor: 5.209

6.  Is repair preferable to replacement for ischemic mitral regurgitation?

Authors:  A M Gillinov; P N Wierup; E H Blackstone; E S Bishay; D M Cosgrove; J White; B W Lytle; P M McCarthy
Journal:  J Thorac Cardiovasc Surg       Date:  2001-12       Impact factor: 5.209

7.  Does coronary artery bypass grafting alone correct moderate ischemic mitral regurgitation?

Authors:  L Aklog; F Filsoufi; K Q Flores; R H Chen; L H Cohn; N S Nathan; J G Byrne; D H Adams
Journal:  Circulation       Date:  2001-09-18       Impact factor: 29.690

8.  Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler assessment.

Authors:  F Grigioni; M Enriquez-Sarano; K J Zehr; K R Bailey; A J Tajik
Journal:  Circulation       Date:  2001-04-03       Impact factor: 29.690

9.  Outcomes and long-term survival for patients undergoing mitral valve repair versus replacement: effect of age and concomitant coronary artery bypass grafting.

Authors:  Vinod H Thourani; William S Weintraub; Robert A Guyton; Ellis L Jones; Willis H Williams; Sharif Elkabbani; Joseph M Craver
Journal:  Circulation       Date:  2003-06-30       Impact factor: 29.690

10.  Mild to moderate mitral regurgitation in patients undergoing coronary bypass grafting: effects on operative mortality and long-term significance.

Authors:  Domenico Paparella; Lynda L Mickleborough; Susan Carson; Joan Ivanov
Journal:  Ann Thorac Surg       Date:  2003-10       Impact factor: 4.330

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  6 in total

1.  Contemporary outcomes for surgical mitral valve repair: a benchmark for evaluating emerging mitral valve technology.

Authors:  Damien J LaPar; Daniel P Mulloy; Ivan K Crosby; D Scott Lim; John A Kern; Irving L Kron; Gorav Ailawadi
Journal:  J Thorac Cardiovasc Surg       Date:  2012-02-11       Impact factor: 5.209

2.  Ex Vivo Model of Ischemic Mitral Regurgitation and Analysis of Adjunctive Papillary Muscle Repair.

Authors:  Annabel M Imbrie-Moore; Yuanjia Zhu; Tabitha Bandy-Vizcaino; Matthew H Park; Robert J Wilkerson; Y Joseph Woo
Journal:  Ann Biomed Eng       Date:  2021-11-03       Impact factor: 4.219

Review 3.  Mitral Valve Repair: The French Correction Versus the American Correction.

Authors:  Sarah A Schubert; James H Mehaffey; Eric J Charles; Irving L Kron
Journal:  Surg Clin North Am       Date:  2017-08       Impact factor: 2.741

4.  The viable mitral annular dynamics and left ventricular function after mitral valve repair by biological rings.

Authors:  Farideh Roshanali; Ali Vedadian; Saeed Shoar; Saleh Sandoughdaran; Mohammad Naderan; Mohammad Hossein Mandegar
Journal:  Int Cardiovasc Res J       Date:  2012-12-15

5.  Mitral valve restoration using the No-React(R) MitroFix™: a novel concept.

Authors:  Frank Oertel; Karl Golczyk; Sigrun Pantele; Vladimir Danov; Manuel Galiñanes; Michael Beyer
Journal:  J Cardiothorac Surg       Date:  2012-09-04       Impact factor: 1.637

Review 6.  Ischemic mitral regurgitation.

Authors:  Praveen Kerala Varma; Neethu Krishna; Reshmi Liza Jose; Ashish Narayan Madkaiker
Journal:  Ann Card Anaesth       Date:  2017 Oct-Dec
  6 in total

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