Literature DB >> 21245476

A novel method to enhance informed consent: a prospective and randomised trial of form-based versus electronic assisted informed consent in paediatric endoscopy.

Joel A Friedlander1, Greg S Loeben, Patricia K Finnegan, Anita E Puma, Xuemei Zhang, Edwin F de Zoeten, David A Piccoli, Petar Mamula.   

Abstract

OBJECTIVES: To evaluate the adequacy of paediatric informed consent and its augmentation by a supplemental computer-based module in paediatric endoscopy.
METHODS: The Consent-20 instrument was developed and piloted on 47 subjects. Subsequently, parents of 101 children undergoing first-time, diagnostic upper endoscopy performed under moderate IV sedation were prospectively and consecutively, blinded, randomised and enrolled into two groups that received either standard form-based informed consent or standard form-based informed consent plus a commercial (Emmi Solutions, Inc, Chicago, Il), sixth grade level, interactive learning module (electronic assisted consent). Anonymously and electronically, the subjects' anxiety (State Trait Anxiety Inventory), satisfaction (Modified Group Health Association of America), number of questions asked, and attainment of informed consent were assessed (Consent-20). Statistics were calculated using t test, paired t test, and Mann Whitney tests.
RESULTS: The ability to achieve informed consent, as measured by the new instrument, was 10% in the control form-based consent group and 33% in the electronic assisted consent group (p<0.0001). Electronically assisting form-based informed consent did not alter secondary outcome measures of subject satisfaction, anxiety or number of questions asked in a paediatric endoscopy unit.
CONCLUSIONS: This study demonstrates the limitations of form-based informed consent methods for paediatric endoscopy. It also shows that even when necessary information was repeated electronically in a comprehensive and standardised video, informed consent as measured by our instrument was incompletely achieved. The supplemental information did, however, significantly improve understanding in a manner that did not negatively impact workflow, subject anxiety or subject satisfaction. Additional study of informed consent is required.

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Year:  2011        PMID: 21245476     DOI: 10.1136/jme.2010.037622

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  9 in total

Review 1.  Informed consent for clinical treatment.

Authors:  Daniel E Hall; Allan V Prochazka; Aaron S Fink
Journal:  CMAJ       Date:  2012-03-05       Impact factor: 8.262

2.  Building an Informed Consent Tool Starting with the Patient: The Patient-Centered Virtual Multimedia Interactive Informed Consent (VIC).

Authors:  Fuad Abujarad; Sandra Alfano; Tiffani J Bright; Sneha Kannoth; Nicole Grant; Matthew Gueble; Peter Peduzzi; Geoffrey Chupp
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

3.  Evaluation of a REDCap-based Workflow for Supporting Federal Guidance for Electronic Informed Consent.

Authors:  Cindy Chen; Scott P Turner; Evan T Sholle; Scott W Brown; Vanessa L I Blau; Julianna P Brouwer; Alicia N Lewis; Curtis L Cole; David M Nanus; Manish A Shah; John P Leonard; Thomas R Campion
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2019-05-06

4.  Developing and evaluating multimedia information resources to improve engagement of children, adolescents, and their parents with trials (TRECA study): Study protocol for a series of linked randomised controlled trials.

Authors:  Jacqueline Martin-Kerry; Peter Bower; Bridget Young; Jonathan Graffy; Rebecca Sheridan; Ian Watt; Paul Baines; Catherine Stones; Jennifer Preston; Steven Higgins; Carrol Gamble; Peter Knapp
Journal:  Trials       Date:  2017-06-08       Impact factor: 2.279

5.  Online Consent Enables a Randomized, Controlled Trial Testing a Patient-Centered Online Decision-Aid for Medicare Beneficiaries to Meet Recruitment Goal in Short Time Frame.

Authors:  Amy Meehan; Mary Kate Bundorf; Roman Klimke; Cheryl D Stults; Albert S Chan; Ting Pun; Ming Tai-Seale
Journal:  J Patient Exp       Date:  2019-11-26

6.  Comparing a Multimedia Digital Informed Consent Tool With Traditional Paper-Based Methods: Randomized Controlled Trial.

Authors:  Fuad Abujarad; Peter Peduzzi; Sophia Mun; Kristina Carlson; Chelsea Edwards; James Dziura; Cynthia Brandt; Sandra Alfano; Geoffrey Chupp
Journal:  JMIR Form Res       Date:  2021-10-19

7.  Development of a core outcome set for informed consent for therapy: An international key stakeholder consensus study.

Authors:  Liam J Convie; Joshua M Clements; Scott McCain; Jeffrey Campbell; Stephen J Kirk; Mike Clarke
Journal:  BMC Med Ethics       Date:  2022-08-09       Impact factor: 2.834

Review 8.  Remote Methods for Conducting Tobacco-Focused Clinical Trials.

Authors:  Jennifer Dahne; Rachel L Tomko; Erin A McClure; Jihad S Obeid; Matthew J Carpenter
Journal:  Nicotine Tob Res       Date:  2020-12-12       Impact factor: 4.244

9.  A novel metadata management model to capture consent for record linkage in longitudinal research studies.

Authors:  Christiana McMahon; Spiros Denaxas
Journal:  Inform Health Soc Care       Date:  2017-11-06       Impact factor: 2.439

  9 in total

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