Literature DB >> 2124530

Effects of immunomodulating therapy in systemic sclerosis.

F H van den Hoogen1, A M Boerbooms, L B van de Putte.   

Abstract

We reviewed studies concerning immunomodulating therapy in systemic sclerosis. These comprise mostly uncontrolled trials and case reports. Some of these studies hint at a possible beneficial effect of antimetabolites (azathioprine, 5-fluoro-uracil and methotrexate), cyclosporine and interferon-gamma. However, to give a clearcut answer on the efficacy of these drugs in systemic sclerosis, controlled studies are urgently needed.

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Year:  1990        PMID: 2124530     DOI: 10.1007/bf02114391

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  25 in total

1.  The effect of cyclophosphamide on B and T lymphocytes in patients with connective tissue diseases.

Authors:  E R Hurd; V J Giuliano
Journal:  Arthritis Rheum       Date:  1975 Jan-Feb

2.  Methotrexate treatment in scleroderma.

Authors:  F H van den Hoogen; A M Boerbooms; L B van de Putte
Journal:  Am J Med       Date:  1989-07       Impact factor: 4.965

3.  [Scleroderma and Gougerot-Sjögren syndrome. Effect of methotrexate therapy].

Authors:  J Welin; J Y Grolleau; H Barrière
Journal:  Sem Hop Ther       Date:  1973-01

4.  Generalized scleroderma. Treatment with an immunosuppressive agent.

Authors:  G T Jansen; D F Barraza; J L Ballard; W M Honeycutt; C J Dillaha
Journal:  Arch Dermatol       Date:  1968-06

5.  [Long-term, small-dose cyclophosphamide treatment of severe inflammatory joint diseases].

Authors:  Y Chaouat; J Paquet; J Pélisson; B Kanovitch; S Rascovscki
Journal:  Rev Rhum Mal Osteoartic       Date:  1968-12

6.  [So-called immunosuppressive cytotoxic medication in acute disseminated lupus erythematosus and scleroderma].

Authors:  J Thivolet; H Perrot
Journal:  Bull Soc Fr Dermatol Syphiligr       Date:  1970

7.  Cyclosporine in successful control of rapidly progressive scleroderma.

Authors:  T Appelboom; D Itzkowitch
Journal:  Am J Med       Date:  1987-04       Impact factor: 4.965

8.  Scleroderma treated with immunosuppressive drugs.

Authors:  A R Kurwa; A M Denman
Journal:  Br J Dermatol       Date:  1979-07       Impact factor: 9.302

9.  Scleroderma in childhood.

Authors:  B M Ansell; G A Nasseh; E G Bywaters
Journal:  Ann Rheum Dis       Date:  1976-06       Impact factor: 19.103

10.  Immunosuppression with chlorambucil, versus placebo, for scleroderma. Results of a three-year, parallel, randomized, double-blind study.

Authors:  D E Furst; P J Clements; S Hillis; P A Lachenbruch; B L Miller; M G Sterz; H E Paulus
Journal:  Arthritis Rheum       Date:  1989-05
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  1 in total

Review 1.  [Treatment of systemic sclerosis].

Authors:  F H J van den Hoogen
Journal:  Z Rheumatol       Date:  2006-07       Impact factor: 1.372

  1 in total

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