Literature DB >> 21241860

Stage II palliation of hypoplastic left heart syndrome without cardiopulmonary bypass.

Anthony Azakie1, Natalie C Johnson, Petros V Anagnostopoulos, Sami M Akram, Patrick McQuillen, Anil Sapru.   

Abstract

OBJECTIVES: Bidirectional cavopulmonary anastomosis has been performed without cardiopulmonary bypass for some single-ventricle heart defects. Limited data are available for the outcomes of off-pump bidirectional cavopulmonary anastomosis in infants with hypoplastic left heart syndrome. The purpose of this study is to determine the early outcomes for stage II palliation of hypoplastic left heart syndrome without cardiopulmonary bypass.
METHODS: This is a retrospective review of infants having surgical palliation of hypoplastic left heart syndrome from April 2003 to March 2010 at a single institution.
RESULTS: Seventy-five infants had a modified Norwood procedure, 65 with a right ventricle-pulmonary artery conduit, 10 with an aortopulmonary shunt, 2 with atrioventricular valve repair, and 3 with extracorporeal life support. Sixty-eight patients had hypoplastic left heart syndrome or one of its variants, and 7 had other single-ventricle lesions. There were 2 stage I deaths. Stage I survival was 97% (95% confidence interval, 88%-99%). Another 5 infants succumbed in the interstage period. Of the 68 stage I and interstage survivors, 61 had bidirectional cavopulmonary anastomoses, 20 without cardiopulmonary bypass. Median age was 6 months (range, 4-13 months), and median weight was 6.1 kg (range, 5.2-9.0 kg). There were no conversions to cardiopulmonary bypass when off-pump bidirectional cavopulmonary anastomosis was attempted. There were no hospital deaths. Median ventilation duration was 10 hours (range, 6-18 hours), and length of stay was 5 days (range, 4-9 days). Follow-up was available on all infants at a median duration of 17 months (range, 3-43 months), with no unplanned reinterventions.
CONCLUSIONS: Bidirectional cavopulmonary anastomosis without the use of cardiopulmonary bypass can be performed safely and with low mortality for selected infants with hypoplastic left heart syndrome. Midterm to long-term outcomes remain to be determined. Copyright Â
© 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Mesh:

Year:  2011        PMID: 21241860      PMCID: PMC5253184          DOI: 10.1016/j.jtcvs.2010.10.047

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  15 in total

Review 1.  The bidirectional cavopulmonary shunt for hypoplastic left heart syndrome.

Authors:  T R Karl
Journal:  Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu       Date:  2001

2.  Impact of right ventricle to pulmonary artery conduit on outcome of the modified Norwood procedure.

Authors:  Anthony Azakie; Daniel Martinez; Anil Sapru; Jeffrey Fineman; David Teitel; Tom R Karl
Journal:  Ann Thorac Surg       Date:  2004-05       Impact factor: 4.330

3.  Cerebral oxygen balance is impaired during repair of aortic coarctation in infants and children.

Authors:  Anthony Azakie; Jessica Muse; Marisa Gardner; Kimberly L Skidmore; Steven P Miller; Tom R Karl; Patrick S McQuillen
Journal:  J Thorac Cardiovasc Surg       Date:  2005-09       Impact factor: 5.209

4.  Survival after bidirectional cavopulmonary anastomosis: analysis of preoperative risk factors.

Authors:  Mark A Scheurer; Elizabeth G Hill; Nagavardhan Vasuki; Scott Maurer; Eric M Graham; Varsha Bandisode; Girish S Shirali; Andrew M Atz; Scott M Bradley
Journal:  J Thorac Cardiovasc Surg       Date:  2007-07       Impact factor: 5.209

5.  Regional and central venous oxygen saturation monitoring following pediatric cardiac surgery: concordance and association with clinical variables.

Authors:  Patrick S McQuillen; Michael S Nishimoto; Christine L Bottrell; Lori D Fineman; Shannon E Hamrick; David V Glidden; Anthony Azakie; Ian Adatia; Steven P Miller
Journal:  Pediatr Crit Care Med       Date:  2007-03       Impact factor: 3.624

6.  Novel techniques of bidirectional Glenn shunt without cardiopulmonary bypass.

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Journal:  Ann Thorac Surg       Date:  1999-06       Impact factor: 4.330

7.  Physiologic repair of aortic atresia-hypoplastic left heart syndrome.

Authors:  W I Norwood; P Lang; D D Hansen
Journal:  N Engl J Med       Date:  1983-01-06       Impact factor: 91.245

8.  The bidirectional cavopulmonary shunt.

Authors:  J J Lamberti; R L Spicer; J D Waldman; T M Grehl; D Thomson; L George; S E Kirkpatrick; J W Mathewson
Journal:  J Thorac Cardiovasc Surg       Date:  1990-07       Impact factor: 5.209

9.  Early cavopulmonary anastomosis in very young infants after the Norwood procedure: impact on oxygenation, resource utilization, and mortality.

Authors:  Robert D B Jaquiss; Nancy S Ghanayem; George M Hoffman; Raymond T Fedderly; Joseph R Cava; Kathleen A Mussatto; James S Tweddell
Journal:  J Thorac Cardiovasc Surg       Date:  2004-04       Impact factor: 5.209

10.  Right ventricle-pulmonary artery shunt in first-stage palliation of hypoplastic left heart syndrome.

Authors:  Shunji Sano; Kozo Ishino; Masaaki Kawada; Sadahiko Arai; Shingo Kasahara; Tomohiro Asai; Zen-ichi Masuda; Mamoru Takeuchi; Shin-ichi Ohtsuki
Journal:  J Thorac Cardiovasc Surg       Date:  2003-08       Impact factor: 5.209

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  1 in total

1.  Risk factors for prolonged length of stay after the stage 2 procedure in the single-ventricle reconstruction trial.

Authors:  Steven M Schwartz; Minmin Lu; Richard G Ohye; Kevin D Hill; Andrew M Atz; Maryam Y Naim; Ismee A Williams; Caren S Goldberg; Alan Lewis; Frank Pigula; Peter Manning; Christian Pizarro; Paul Chai; Rachel McCandless; Carolyn Dunbar-Masterson; Jonathan R Kaltman; Kirk Kanter; Lynn A Sleeper; Julie V Schonbeck; Nancy Ghanayem
Journal:  J Thorac Cardiovasc Surg       Date:  2013-09-24       Impact factor: 5.209

  1 in total

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