Literature DB >> 21241438

Portal vein obstruction after liver transplantation in children treated by simultaneous minilaparotomy and transhepatic approaches: initial experience.

Francisco C Carnevale1, Aline C B Santos, João Seda-Neto, Charles E Zurstrassen, Airton M Moreira, Eduardo Carone, Antonio S Z Marcelino, Gilda Porta, Renata Pugliese, Irene Miura, Vera D Baggio, Teresa Guimarães, Giovanni G Cerri, Paulo Chapchap.   

Abstract

Portal vein thrombosis is a complication that occurs anytime after liver transplantation and can compromise the patient and graft survival. We describe a combined technique for PV recanalization in cases of PV obstruction after liver transplantation. Four children (1%), of 367 subjected to liver transplantation from June 1991 to December 2008, underwent PV recanalization through a combined approach (transhepatic and minilaparotomy). All children received left lateral hepatic segments, developed Portal vein thrombosis (n=3) and stenosis (n=1), and presented with symptoms of portal hypertension after transplantation. PV recanalization was tried by transhepatic retrograde access, and a minilaparotomy was performed when percutaneous recanalization was unsuccessful. Three patients underwent a successful portal recanalization and stent placement with the combined technique. In one patient, the recanalization was unsuccessful because of an extensive portomesenteric thrombosis. The other three children had the portal flow reestablished and followed with Doppler US studies. They received oral anticoagulation for three consecutive months after the procedure and the clinical symptoms subsided. In case of PV obstruction, the combined approach is technically feasible with good clinical and hemodynamic results. It' is a minimally invasive procedure and can be tried to avoid or delay surgical treatment or retransplantation.
© 2011 John Wiley & Sons A/S.

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Year:  2011        PMID: 21241438     DOI: 10.1111/j.1399-3046.2010.01350.x

Source DB:  PubMed          Journal:  Pediatr Transplant        ISSN: 1397-3142


  3 in total

1.  Percutaneous Transhepatic Approach for Recanalization of Superior Mesenteric and Portal Vein in a Patient With Pancreatic Neuroendocrine Tumor Presenting With Bleeding Duodenal Varices: A Brief Case Report.

Authors:  Ajit Yadav; Gaurav Gangwani; Nitin Mishra; Arun Gupta
Journal:  J Clin Exp Hepatol       Date:  2018-03-30

2.  One step minilaparotomy-assisted transmesenteric portal vein recanalization combined with transjugular intrahepatic portosystemic shunt placement: A novel surgical proposal in pediatrics.

Authors:  Gloria Pelizzo; Pietro Quaretti; Lorenzo Paolo Moramarco; Riccardo Corti; Marcello Maestri; Giulio Iacob; Valeria Calcaterra
Journal:  World J Gastroenterol       Date:  2017-04-21       Impact factor: 5.742

3.  Outcomes of Liver Transplantation in Small Infants.

Authors:  Hidekazu Yamamoto; Shirin E Khorsandi; Miriam Cortes-Cerisuelo; Yoichi Kawano; Anil Dhawan; John McCall; Hector Vilca-Melendez; Mohamed Rela; Nigel Heaton
Journal:  Liver Transpl       Date:  2019-10       Impact factor: 5.799

  3 in total

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