Literature DB >> 21241196

Dexmedetomidine as an adjuvant analgesic for intractable cancer pain.

Seth B Roberts1, Colin P Wozencraft, Patrick J Coyne, Thomas J Smith.   

Abstract

Abstract Dexmedetomidine (Precedex®) is an alpha-2 adrenergic agonist that can produce sedation and analgesia without causing respiratory depression. Its use has been described in patients undergoing mechanical ventilation, sedation for surgical and nonsurgical procedures, and prevention of withdrawal. We describe its use as an adjuvant analgesic in a patient with cancer pain refractory to multiple treatment modalities.

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Year:  2011        PMID: 21241196     DOI: 10.1089/jpm.2010.0235

Source DB:  PubMed          Journal:  J Palliat Med        ISSN: 1557-7740            Impact factor:   2.947


  9 in total

1.  Applications of Dexmedetomidine in Palliative and Hospice Care.

Authors:  Rafael Lemus; Natalie L Jacobowski; Lisa Humphrey; Joseph D Tobias
Journal:  J Pediatr Pharmacol Ther       Date:  2022-09-26

2.  Effect of sedation on pain perception.

Authors:  Michael A Frölich; Kui Zhang; Timothy J Ness
Journal:  Anesthesiology       Date:  2013-03       Impact factor: 7.892

3.  The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure.

Authors:  Mercedes J Szpunar; Kathleen A Burke; Ryan P Dawes; Edward B Brown; Kelley S Madden
Journal:  Cancer Prev Res (Phila)       Date:  2013-12

4.  Dexmedetomidine upregulates microRNA-185 to suppress ovarian cancer growth via inhibiting the SOX9/Wnt/β-catenin signaling pathway.

Authors:  Hang Tian; Lei Hou; Yumei Xiong; Qiuju Cheng
Journal:  Cell Cycle       Date:  2021-04-04       Impact factor: 4.534

5.  Dexmedetomidine: New avenues.

Authors:  Anju Grewal
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2011-07

6.  Post-operative analgesic effect of dexmedetomidine administration in wound infiltration for abdominal hysterectomy: A randomised control study.

Authors:  Swati Singh; Chandrakant Prasad
Journal:  Indian J Anaesth       Date:  2017-06

Review 7.  Dexmedetomidine: an adjuvant making large inroads into clinical practice.

Authors:  Sj Bajwa; A Kulshrestha
Journal:  Ann Med Health Sci Res       Date:  2013-10

8.  Successful Treatment of Refractory Cancer Pain and Depression with Continuous Intrathecal Administration of Dexmedetomidine and Morphine: A Case Report.

Authors:  Ge Huang; Guo Liu; Zhiguo Zhou; Jinfeng Yang; Chen Su
Journal:  Pain Ther       Date:  2020-07-12

9.  Is Spinal Dexmedetomidine Aggravating Hypotension after Tourniquet Deflation?

Authors:  Mohamed Maher El Baz; Ahmed Mohamed Farid
Journal:  Anesth Essays Res       Date:  2021-03-22
  9 in total

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