Literature DB >> 21240679

Constituents of cultivated Agaricus blazei.

Yumi Ueguchi1, Katsuyoshi Matsunami, Hideaki Otsuka, Kazunari Kondo.   

Abstract

Two phenylhexane derivatives (1, 2), benzoylergostane (3), N-benzoyl-L-leucine methyl ester (4), two known ergostanes, and highly degraded incisterol were isolated from fruit bodies of Agaricus blazei. Compound 3 exhibited strong cytotoxicity toward HepG2 cells (IC(50) = 6.0 ± 0.33 μM).

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Year:  2011        PMID： 21240679     DOI： 10.1007/s11418-010-0495-5

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  13 in total

1.  Clinical trial of the oral form of a new podophyllotoxin derivative, VP-16-213 (NSC-141540), in patients with advanced neoplastic disease.

Authors:  N I Nissen; H H Hansen; H Pedersen; I Stroyer; P Dombernowsky; M Hessellund
Journal:  Cancer Chemother Rep       Date:  1975 Sep-Oct

2.  Sterols from the fungus Lactarium volemus.

Authors:  J M Yue; S N Chen; Z W Lin; H D Sun
Journal:  Phytochemistry       Date:  2001-04       Impact factor: 4.072

3.  Activity of a new glycosidic lignan derivative (VP 16-213) related to podophyllotoxin in experimental tumors.

Authors:  H Stähelin
Journal:  Eur J Cancer       Date:  1973-03       Impact factor: 9.162

4.  Cytotoxic sterol derivatives from a marine sponge Homaxinella sp.

Authors:  Tayyab A Mansoor; Jongki Hong; Chong-O Lee; Song-Ja Bae; Kwang Sik Im; Jee H Jung
Journal:  J Nat Prod       Date:  2005-03       Impact factor: 4.050

5.  An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients.

Authors:  Hirofumi Mukai; Toru Watanabe; Masashi Ando; Noriyuki Katsumata
Journal:  Jpn J Clin Oncol       Date:  2006-11-14       Impact factor: 3.019

6.  Screening for in vitro and in vivo antitumor activities of the mushroom Agaricus blazei.

Authors:  Liane Ziliotto; Fabriciano Pinheiro; Luís Fernando Barbisan; Maria Aparecida Marchesan Rodrigues
Journal:  Nutr Cancer       Date:  2009       Impact factor: 2.900

7.  Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions.

Authors:  Yoshiyuki Kimura; Tadashi Kido; Takeshi Takaku; Maho Sumiyoshi; Kimiye Baba
Journal:  Cancer Sci       Date:  2004-09       Impact factor: 6.716

Review 8.  Etoposide (VP-16-213).

Authors:  B F Issell; S T Crooke
Journal:  Cancer Treat Rev       Date:  1979-06       Impact factor: 12.111

9.  Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells.

Authors:  Hiroko Itoh; Hitoshi Ito; Hiroshige Hibasami
Journal:  Oncol Rep       Date:  2008-12       Impact factor: 3.906

10.  The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems.

Authors:  F Firenzuoli; L Gori; G Lombardo
Journal:  Evid Based Complement Alternat Med       Date:  2008-03       Impact factor: 2.629
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  1 in total

1.  Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.

Authors:  Mengyu Sun; Dongdong Zhou; Jingwan Wu; Jing Zhou; Jing Xu
Journal:  Mar Drugs       Date:  2022-02-05       Impact factor: 5.118
  1 in total

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