| Literature DB >> 21240343 |
S A Kryzhanovskyi1, A V Sorokina, V N Stolyaruck, M B Vititnova, I A Miroshkina, I B Tsorin, A D Durnev, S B Seredenin.
Abstract
Seven-day treatment of rats with experimental myocardial infarction with afobazole (5-ethoxy-2-[2-morpholino)-ethylthio] benzimidasole dihydrochloride) resulted in shrinkage of the ischemic damage area in the heart, stimulation of reparative processes in the myocardium, and prevention of postinfarction remodeling of the left ventricle. Anti-ischemic effect of afobazole in experimental myocardial infarction is presumably due to its interactions with σ(1) receptors.Entities:
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Year: 2011 PMID： 21240343 DOI： 10.1007/s10517-011-1131-4
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804