Kabunda Syebele1, Kurt-W Bütow. 1. Department of Maxillofacial and Oral Surgery, University Of Pretoria, Pretoria, South Africa. kabunda.syebele@up.ac.za
Abstract
OBJECTIVE: This study's aim was to assess the effect of highly active antiretroviral drugs (HAART) on benign lymphoepithelial cysts (BLEC) of the parotid and ranulas. STUDY DESIGN: The records of 10 HIV-positive patients who presented with BLEC were reviewed, and 14 HIV-positive patients who presented with ranulas were prospectively enrolled. Patients in both groups received the same combination of HAART and were clinically evaluated for the first 3 months. Patients with ranulas were followed for an additional 3 months. A clinical reduction in the size of the lesions was considered to be a positive outcome. RESULTS: All parotid glands with BLEC resolved within 3 months. No positive results were observed in ranulas during the first 3 months. However, some of the ranulas displayed a positive result after the initial 3 months of HAART. CONCLUSIONS: In contrast to BLEC, ranulas in HIV-positive patients seem to present a mixed and delayed response to HAART.
OBJECTIVE: This study's aim was to assess the effect of highly active antiretroviral drugs (HAART) on benign lymphoepithelial cysts (BLEC) of the parotid and ranulas. STUDY DESIGN: The records of 10 HIV-positivepatients who presented with BLEC were reviewed, and 14 HIV-positivepatients who presented with ranulas were prospectively enrolled. Patients in both groups received the same combination of HAART and were clinically evaluated for the first 3 months. Patients with ranulas were followed for an additional 3 months. A clinical reduction in the size of the lesions was considered to be a positive outcome. RESULTS: All parotid glands with BLEC resolved within 3 months. No positive results were observed in ranulas during the first 3 months. However, some of the ranulas displayed a positive result after the initial 3 months of HAART. CONCLUSIONS: In contrast to BLEC, ranulas in HIV-positivepatients seem to present a mixed and delayed response to HAART.
Authors: Waleed F Mourad; Shyamal Patel; Rebekah Young; Azita S Khorsandi; Catherine Concert; Rania A Shourbaji; Katherine Ciarrocca; Richard L Bakst; Daniel Shasha; Chandan Guha; Madhur K Garg; Kenneth S Hu; Shalom Kalnicki; Louis B Harrison Journal: Eur Arch Otorhinolaryngol Date: 2016-02-16 Impact factor: 2.503