| Literature DB >> 21237182 |
Jiangang Liu1, Jun Li2, Cory A Rieth3, David E Huber3, Jie Tian4, Kang Lee5.
Abstract
The present study employed dynamic causal modeling to investigate the effective functional connectivity between regions of the neural network involved in top-down letter processing. We used an illusory letter detection paradigm in which participants detected letters while viewing pure noise images. When participants detected letters, the response of the right middle occipital gyrus (MOG) in the visual cortex was enhanced by increased feed-backward connectivity from the left inferior frontal gyrus (IFG). In addition, illusory letter detection increased feed-forward connectivity from the right MOG to the left inferior parietal lobules. Originating in the left IFG, this top-down letter processing network may facilitate the detection of letters by activating letter processing areas within the visual cortex. This activation in turns may highlight the visual features of letters and send letter information to activate the associated phonological representations in the identified parietal region.Entities:
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Year: 2011 PMID： 21237182 PMCID： PMC3817006 DOI： 10.1016/j.neuropsychologia.2011.01.011
Source DB: PubMed Journal: Neuropsychologia ISSN： 0028-3932 Impact factor: 3.139