Topical Acyclovir for Recurrent Herpes Labialis in Primary Care: Critical appraisal.

I reviewed the literature on the treatment of recurrent herpes labialis with topical acyclovir ointment to determine the effectiveness of this treatment for family practice patients. This article discusses the generalizability of the results to family practice. I concluded that the evidence supporting this therapy is weak and that it cannot, in the light of current knowledge, be strongly recommended.