Literature DB >> 2123369

Contraceptive vaginal ring--a rising star on the contraceptive horizon.

K Buckshee1, S Kumar, L Saraya.   

Abstract

Two studies were carried out at AIIMS to judge efficacy, side-effects and acceptability of the contraceptive vaginal ring, a Silastic ring with an inner core containing 6.0 mg levonorgestrel mixed with Silastic and an outer core of Silastic only. It releases levonorgestrel at a constant rate of 20 micrograms/day and remains effective for 90 days. The first study of 50 women lasted for 12 months and the second study of 46 women lasted 24 months. Menstrual irregularity in 36% of women was the commonest reason for discontinuation. The majority of women experienced menorrhagia or irregular spotting per vaginum. Vaginal irritation or increased vaginal discharge was the second commonest reason for discontinuation and was noted in 23% of subjects. Repeated spontaneous expulsions accounted for discontinuation in 6% of subjects. No method-related failure was noted in the study. Follow-up study revealed users to be happier with the ring than with any other method and no spouse complained of feeling the ring during coitus. With its ease of administration, absence of gastrointestinal side-effects and a high success rate, the contraceptive vaginal ring is a promising contraceptive method for the last decade of the 20th century.

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Year:  1990        PMID: 2123369     DOI: 10.1007/bf01849492

Source DB:  PubMed          Journal:  Adv Contracept        ISSN: 0267-4874


  6 in total

Review 1.  Current status of fertility control methods in India.

Authors:  R S Sharma; M Rajalakshmi; R S Sharma; D A Jeyaraj
Journal:  J Biosci       Date:  2001-11       Impact factor: 1.826

2.  Vaginal ring acceptability: A systematic review and meta-analysis of vaginal ring experiences from around the world.

Authors:  Kathleen Ridgeway; Elizabeth T Montgomery; Kevin Smith; Kristine Torjesen; Ariane van der Straten; Sharon L Achilles; Jennifer B Griffin
Journal:  Contraception       Date:  2021-10-10       Impact factor: 3.051

3.  Controlled release of contraceptive steroids from biodegradable and injectable gel formulations: in vivo evaluation.

Authors:  Z H Gao; W R Crowley; A J Shukla; J R Johnson; J F Reger
Journal:  Pharm Res       Date:  1995-06       Impact factor: 4.200

4.  Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis.

Authors:  Jennifer B Griffin; Kathleen Ridgeway; Elizabeth Montgomery; Kristine Torjesen; Rachel Clark; Jill Peterson; Rachel Baggaley; Ariane van der Straten
Journal:  PLoS One       Date:  2019-11-08       Impact factor: 3.240

Review 5.  Acceptability and Satisfaction of Contraceptive Vaginal Rings in Clinical Studies: A Systematic Review and Narrative Synthesis.

Authors:  Thérèse Delvaux; Vicky Jespers; Lenka Benova; Janneke van de Wijgert
Journal:  Front Glob Womens Health       Date:  2021-12-14

6.  Optimizing adherence in HIV prevention product trials: Development and psychometric evaluation of simple tools for screening and adherence counseling.

Authors:  Elizabeth E Tolley; Kate Morrow Guthrie; Seth Zissette; Joseph L Fava; Katherine Gill; Cheryl E Louw; Philip Kotze; Krishnaveni Reddy; Kathleen MacQueen
Journal:  PLoS One       Date:  2018-04-12       Impact factor: 3.240

  6 in total

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