Literature DB >> 21229459

SnCl4 · 5H2O-catalyzed synthesis of β-amino carbonyl compounds via a direct Mannich-type reaction.

Min Wang1, Zhiguo Song, Yan Liang.   

Abstract

An efficient three-component, one-pot synthesis of β-amino carbonyl compounds from aromatic ketones, aromatic aldehydes, and aromatic amines using tin tetrachloride at room temperature in ethanol is described. The advantages of the new method are good yields (62-96%), simple workup, and inexpensive catalyst.

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Year:  2011        PMID: 21229459     DOI: 10.1080/10826068.2010.489008

Source DB:  PubMed          Journal:  Prep Biochem Biotechnol        ISSN: 1082-6068            Impact factor:   2.162


  1 in total

1.  Hf(OTf)4 as a Highly Potent Catalyst for the Synthesis of Mannich Bases under Solvent-Free Conditions.

Authors:  Shuai-Bo Han; Jing-Ying Wei; Xiao-Chong Peng; Rong Liu; Shan-Shan Gong; Qi Sun
Journal:  Molecules       Date:  2020-01-17       Impact factor: 4.411

  1 in total

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