Treatment of Asymptomatic Hyperuricemia: When do you have a good reason to provide therapy?

Treatment of asymptomatic hyperuricemia to prevent gout, renal failure, or kidney stones is not justified. Similarly, the risks of developing either renal failure or kidney stones as a consequence of asymptomatic hyperuricemia are extremely low and do not justify intervention. Only in tumor lysis syndromes is therapy to prevent acute renal failure logical. Serum urate measurement should be requested in only very limited clinical circumstances.