Literature DB >> 21226

Varicella-zoster virus-induced DNA polymerase.

R L Miller, F Rapp.   

Abstract

Nuclear extracts of varicella-zoster virus (VZV)-infected human embryo lung (HEL) cells were found to contain DNA polymerase activity not present in uninfected HEL cells. This enzyme was designated the VZV-induced DNA polymerase. The VZV-induced polymerase was partially separated from the cellular alpha- and beta-polymerases by fractionation of the cells and by phosphocellulose chromatography. The separated enzymes were examined for the effect of added (NH4)2SO4, activity with synthetic templates, optimal pH, and the effect of phosphonoacetic acid. The VZV-induced DNA polymerase was distinct from cellular enzymes and had the properties of a typical herpesvirus-induced DNA polymerase.

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Year:  1977        PMID： 21226     DOI： 10.1099/0022-1317-36-3-515

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  7 in total

1.  Purification and characterization of varicella-zoster virus-induced DNA polymerase.

Authors:  E C Mar; Y S Huang; E S Huang
Journal:  J Virol       Date:  1978-05       Impact factor: 5.103

2.  Characterization of an Epstein-Barr virus-induced DNA polymerase.

Authors:  T Ooka; G Lenoir; J Daillie
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

3.  In vitro susceptibility of varicella-zoster virus to acyclovir.

Authors:  K K Biron; G B Elion
Journal:  Antimicrob Agents Chemother       Date:  1980-09       Impact factor: 5.191

4.  Virus replication and localization of varicella-zoster virus antigens in human embryonic fibroblast cells infected with cell-free virus.

Authors:  K Yamanishi; Y Matsunaga; T Ogino; M Takahashi; A Takamizawa
Journal:  Infect Immun       Date:  1980-05       Impact factor: 3.441

5.  Inhibition of varicella-zoster virus-induced DNA polymerase by a new guanosine analog, 9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine triphosphate.

Authors:  G Abele; B Eriksson; J Harmenberg; B Wahren
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

6.  A novel DNA polymerase induced by Bacillus subtilis phage phi 29.

Authors:  K Watabe; J Ito
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971

7.  Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells.

Authors:  P F Ertl; K L Powell
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103
  7 in total

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