Literature DB >> 21225284

Respiratory morbidity, healthcare utilisation and cost of care at school age related to home oxygen status.

Anne Greenough1, John Alexander, Jill Boorman, Philip A J Chetcuti, Ian Cliff, Warren Lenney, Colin Morgan, Nigel J Shaw, Karl P Sylvester, Jackie Turner.   

Abstract

UNLABELLED: The aim of the study was to determine whether respiratory morbidity, lung function, healthcare utilisation and cost of care at school age in prematurely born children who had bronchopulmonary dysplasia (BPD) were influenced by use of supplementary oxygen at home after neonatal intensive care unit discharge. Healthcare utilisation and cost of care in years 5 to 7 and respiratory morbidity (parent-completed respiratory questionnaire) and lung function measurements at least at age 8 years were assessed in 160 children. Their median gestational age was 27 (range 22-31) weeks and 65 of them had received supplementary oxygen when discharged home (home oxygen group). The home oxygen group had more outpatient attendances (p = 0.0168) and respiratory-related outpatient attendances (p = 0.0032) with greater related cost of care (p = 0.0186 and p = 0.0030, respectively), their cost of care for prescriptions (p = 0.0409) and total respiratory related cost of care (p = 0.0354) were significantly greater. There were, however, no significant differences in cough, wheeze or lung function results between the two groups.
CONCLUSION: Prematurely born children who had BPD and supplementary oxygen at home after discharge had increased healthcare utilisation at school age. Whether such children require greater follow, in the absence of excess respiratory morbidity, merits investigation.

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Year:  2011        PMID: 21225284     DOI: 10.1007/s00431-010-1381-6

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  20 in total

Review 1.  Antenatal factors and the development of bronchopulmonary dysplasia.

Authors:  Alan H Jobe
Journal:  Semin Neonatol       Date:  2003-02

2.  Cold air and exercise challenge -- influence of minute ventilation.

Authors:  Karl P Sylvester; Brian J O'Connor; Helen M Farebrother; Gerrard F Rafferty; Anne Greenough
Journal:  J Asthma       Date:  2007-03       Impact factor: 2.515

3.  Home oxygen status and rehospitalisation and primary care requirements of infants with chronic lung disease.

Authors:  A Greenough; J Alexander; S Burgess; P A J Chetcuti; S Cox; W Lenney; F Turnbull; N J Shaw; A Woods; J Boorman; S Coles; J Turner
Journal:  Arch Dis Child       Date:  2002-01       Impact factor: 3.791

4.  Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs.

Authors:  K E Willet; A H Jobe; M Ikegami; J Newnham; S Brennan; P D Sly
Journal:  Pediatr Res       Date:  2000-12       Impact factor: 3.756

5.  Lung function in white children aged 4 to 19 years: II--Single breath analysis and plethysmography.

Authors:  M Rosenthal; D Cramer; S H Bain; D Denison; A Bush; J O Warner
Journal:  Thorax       Date:  1993-08       Impact factor: 9.139

6.  Preschool healthcare utilisation related to home oxygen status.

Authors:  A Greenough; J Alexander; S Burgess; J Bytham; P A J Chetcuti; J Hagan; W Lenney; S Melville; N J Shaw; J Boorman; S Coles; F Pang; J Turner
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2006-05-16       Impact factor: 5.747

7.  Respiratory health in pre-school and school age children following extremely preterm birth.

Authors:  E M Hennessy; M A Bracewell; N Wood; D Wolke; Kate Costeloe; A Gibson; N Marlow
Journal:  Arch Dis Child       Date:  2008-06-18       Impact factor: 3.791

8.  School age outcome of hospitalisation with respiratory syncytial virus infection of prematurely born infants.

Authors:  A Greenough; J Alexander; P Boit; J Boorman; S Burgess; A Burke; P A Chetcuti; I Cliff; W Lenney; T Lytle; C Morgan; C Raiman; N J Shaw; K P Sylvester; J Turner
Journal:  Thorax       Date:  2009-02-12       Impact factor: 9.139

9.  Lung function in white children aged 4 to 19 years: I--Spirometry.

Authors:  M Rosenthal; S H Bain; D Cramer; P Helms; D Denison; A Bush; J O Warner
Journal:  Thorax       Date:  1993-08       Impact factor: 9.139

10.  High versus restricted use of home oxygen therapy, health care utilisation and the cost of care in chronic lung disease infants.

Authors:  Anne Greenough; John Alexander; Sal Burgess; Phillip A J Chetcuti; Sarah Cox; Warren Lenney; Francis Turnbull; Nigel J Shaw; Alison Woods; Jill Boorman; Stephen Coles; Jackie Turner
Journal:  Eur J Pediatr       Date:  2004-06       Impact factor: 3.183

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  9 in total

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Authors:  Sara B DeMauro; Erik A Jensen; Carla M Bann; Edward F Bell; Anna Maria Hibbs; Susan R Hintz; Scott A Lorch
Journal:  Pediatrics       Date:  2019-04-11       Impact factor: 7.124

2.  Health Care and Societal Costs of Bronchopulmonary Dysplasia.

Authors:  Wannasiri Lapcharoensap; Henry C Lee; Amy Nyberg; Dmitry Dukhovny
Journal:  Neoreviews       Date:  2018-04

3.  Does chronic oxygen dependency in preterm infants with bronchopulmonary dysplasia at NICU discharge predict respiratory outcomes at 3 years of age?

Authors:  A Lodha; K Ediger; Y Rabi; S Lodha; S Tang; A Bhandari; R Sauve; V Bhandari
Journal:  J Perinatol       Date:  2015-02-26       Impact factor: 2.521

4.  Home Oxygen Use and 1-Year Readmission among Infants Born Preterm with Bronchopulmonary Dysplasia Discharged from Children's Hospital Neonatal Intensive Care Units.

Authors:  Joanne Lagatta; Karna Murthy; Isabella Zaniletti; Stephanie Bourque; William Engle; Rebecca Rose; Namasivayam Ambalavanan; David Brousseau
Journal:  J Pediatr       Date:  2020-02-21       Impact factor: 4.406

Review 5.  Should we still use vitamin A to prevent bronchopulmonary dysplasia?

Authors:  X I Couroucli; J L Placencia; L A Cates; G K Suresh
Journal:  J Perinatol       Date:  2016-05-26       Impact factor: 2.521

6.  Drug therapy trials for the prevention of bronchopulmonary dysplasia: current and future targets.

Authors:  Vineet Bhandari
Journal:  Front Pediatr       Date:  2014-07-25       Impact factor: 3.418

7.  Respiratory morbidity through the first decade of life in a national cohort of children born extremely preterm.

Authors:  Kaia Skromme; Maria Vollsæter; Knut Øymar; Trond Markestad; Thomas Halvorsen
Journal:  BMC Pediatr       Date:  2018-03-07       Impact factor: 2.125

8.  Impact of a protocol-driven unified service for neonates with bronchopulmonary dysplasia.

Authors:  Natalie Batey; Dushyant Batra; Jon Dorling; Jayesh Mahendra Bhatt
Journal:  ERJ Open Res       Date:  2019-03-25

9.  Gelsolin Attenuates Neonatal Hyperoxia-Induced Inflammatory Responses to Rhinovirus Infection and Preserves Alveolarization.

Authors:  Tracy X Cui; Alexander E Brady; Ying-Jian Zhang; Christina T Fulton; Antonia P Popova
Journal:  Front Immunol       Date:  2022-01-31       Impact factor: 7.561

  9 in total

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