Literature DB >> 21225180

Pleurodesis for malignant pleural effusions: a survey of physicians in South and Central America.

Evaldo Marchi1, Francisco Suso Vargas, Bruna Affonso Madaloso, Marcus Vinicius Carvalho, Ricardo Mingarini Terra, Lisete Ribeiro Teixeira.   

Abstract

OBJECTIVE: Pleurodesis is an effective alternative for the control of malignant pleural effusions. However, there is as yet no consensus regarding the indications for the procedure and the techniques employed therein. The objective of this study was to evaluate how pleurodesis is performed in South and Central America.
METHODS: Professionals who perform pleurodesis completed a questionnaire regarding the indications for the procedure, the techniques used therein, and the outcomes obtained.
RESULTS: Our sample comprised 147 respondents in Brazil, 49 in other South American countries, and 36 in Central America. More than 50% of the respondents reported performing pleurodesis only if pleural malignancy had been confirmed. However, scores on dyspnea and performance status scales were rarely used as indications for the procedure. Nearly 75% of the respondents in Brazil and in Central America preferred to perform pleurodesis only for recurrent effusions and stated that lung expansion should be 90-100%. Talc slurry, instilled via medium-sized chest tubes, was the agent most often employed. Thoracoscopy was performed in less than 25% of cases. Fever and chest pain were the most common side effects, and empyema occurred in < 14% of cases. The mean survival time after the procedure was most often reported to be 6-12 months.
CONCLUSIONS: There was considerable variation among the countries evaluated in terms of the indications for pleurodesis, techniques used, and outcomes. Talc slurry is the agent most commonly used, and thoracoscopy is the technique of choice in Brazil. Pleurodesis is an effective procedure that has few side effects, as evidenced by the low complication rates and high survival times.

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Year:  2010        PMID: 21225180     DOI: 10.1590/s1806-37132010000600014

Source DB:  PubMed          Journal:  J Bras Pneumol        ISSN: 1806-3713            Impact factor:   2.624


  5 in total

Review 1.  Pleurodesis: indications and radiologic appearance.

Authors:  Akinaga Sonoda; Jean Jeudy; Charles S White; Seth J Kligerman; Norihisa Nitta; Jason Lempel; Aletta Ann Frazier
Journal:  Jpn J Radiol       Date:  2015-03-20       Impact factor: 2.374

2.  Sodium hydroxide as a sclerosing agent in patients with neoplastic pleural effusion non-candidates for VATS: results of a minimally invasive protocol.

Authors:  Micaela Raices; Matías E Czerwonko; Agustin Dietrich; Alejandro Da Lozzo; Enrique Beveraggi; David Smith
Journal:  Updates Surg       Date:  2017-08-31

Review 3.  A survey of recently published cardiovascular, hematological and pneumological original articles in the Brazilian scientific press.

Authors:  Kavita Kirankumar Patel; Bruno Caramelli; Ariane Gomes
Journal:  Clinics (Sao Paulo)       Date:  2011       Impact factor: 2.365

4.  Acute pneumonitis consequent on pleurodesis with Viscum album extract: severe chest images but benign clinical course.

Authors:  Suk Ju Cho; Su Wan Kim; Jee Won Chang
Journal:  Multidiscip Respir Med       Date:  2014-11-27

Review 5.  Complications of thoracoscopic talc insufflation for the treatment of malignant pleural effusions: a meta-analysis.

Authors:  Wen Zhang; Yun-Long Zhao; Shao-Jun Li; Ying-Nan Zhao; Nan-Nan Guo; Bo Liu
Journal:  J Cardiothorac Surg       Date:  2021-05-04       Impact factor: 1.637

  5 in total

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