Literature DB >> 21222422

Role of neutrophils in cutaneous leishmaniasis.

M W Daboul1.   

Abstract

Neutrophils are always present in the cytomorphologic process of leishmaniasis but their role is still not fully understood. Microscopic examination was done on smears from 56 cases of clinically diagnosed cutaneous leishmaniasis. Neutrophils were the predominant cells in the smear (> 35% of the total cell count including neutrophils, macrophages and lymphocytes) in 7% of cases, a minority (10%-35% of total cells) in 36% of cases and rare (< 10% of total cells) in 57% of cases. Microscope images confirmed that neutrophils appeared to have an important role in leishmania elimination through phagocytosis of amastigotes in the later stages of the disease process.

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Year:  2010        PMID: 21222422

Source DB:  PubMed          Journal:  East Mediterr Health J        ISSN: 1020-3397            Impact factor:   1.628


  8 in total

Review 1.  Permissive and protective roles for neutrophils in leishmaniasis.

Authors:  E D Carlsen; Y Liang; T R Shelite; D H Walker; P C Melby; L Soong
Journal:  Clin Exp Immunol       Date:  2015-08-28       Impact factor: 4.330

2.  Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance.

Authors:  Eric D Carlsen; Zuliang Jie; Yuejin Liang; Calvin A Henard; Christie Hay; Jiaren Sun; Herbert de Matos Guedes; Lynn Soong
Journal:  J Innate Immun       Date:  2015-02-27       Impact factor: 7.349

3.  Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

Authors:  Eric D Carlsen; Christie Hay; Calvin A Henard; Vsevolod Popov; Nisha Jain Garg; Lynn Soong
Journal:  Infect Immun       Date:  2013-08-05       Impact factor: 3.441

4.  Comparative analysis of the tissue inflammatory response in human cutaneous and disseminated leishmaniasis.

Authors:  Marina Loyola Dantas; Juliana Menezes Gomes Cabral de Oliveira; Lucas Carvalho; Sara Timóteo Passos; Adriano Queiroz; Luiz Henrique Guimarães; Paulo Machado; Edgar Carvalho; Sérgio Arruda
Journal:  Mem Inst Oswaldo Cruz       Date:  2014-03-05       Impact factor: 2.743

5.  A secondary wave of neutrophil infiltration causes necrosis and ulceration in lesions of experimental American cutaneous leishmaniasis.

Authors:  Alex G Peniche; Diana L Bonilla; Gloria I Palma; Peter C Melby; Bruno L Travi; E Yaneth Osorio
Journal:  PLoS One       Date:  2017-06-07       Impact factor: 3.240

Review 6.  Protective or Detrimental? Understanding the Role of Host Immunity in Leishmaniasis.

Authors:  Camila Dos Santos Meira; Lashitew Gedamu
Journal:  Microorganisms       Date:  2019-12-13

7.  Protective and pathologic immune responses in human tegumentary leishmaniasis.

Authors:  Lucas P Carvalho; Sara Passos; Albert Schriefer; Edgar M Carvalho
Journal:  Front Immunol       Date:  2012-10-04       Impact factor: 7.561

Review 8.  Paradoxical immune response in leishmaniasis: The role of toll-like receptors in disease progression.

Authors:  Ifeoluwa E Bamigbola; Selman Ali
Journal:  Parasite Immunol       Date:  2022-02-28       Impact factor: 2.206

  8 in total

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