Literature DB >> 21217667

Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development.

Elisa Araldi, Richa Khatri, Amato J Giaccia, M Celeste Simon, Ernestina Schipani.   

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Year:  2011        PMID： 21217667      PMCID： PMC3215585          DOI： 10.1038/nm0111-25

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  5 in total

1.  Hypoxia, HIFs and bone development.

Authors:  Elisa Araldi; Ernestina Schipani
Journal:  Bone       Date:  2010-05-02       Impact factor: 4.398

2.  Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction.

Authors:  Siyoung Yang; Jonghwan Kim; Je-Hwang Ryu; Hwanhee Oh; Churl-Hong Chun; Byoung Ju Kim; Byoung Hyun Min; Jang-Soo Chun
Journal:  Nat Med       Date:  2010-05-23       Impact factor: 53.440

3.  Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

Authors:  Taku Saito; Atsushi Fukai; Akihiko Mabuchi; Toshiyuki Ikeda; Fumiko Yano; Shinsuke Ohba; Nao Nishida; Toru Akune; Noriko Yoshimura; Takumi Nakagawa; Kozo Nakamura; Katsushi Tokunaga; Ung-Il Chung; Hiroshi Kawaguchi
Journal:  Nat Med       Date:  2010-05-23       Impact factor: 53.440

Review 4.  Hypoxia-inducible factors: central regulators of the tumor phenotype.

Authors:  John D Gordan; M Celeste Simon
Journal:  Curr Opin Genet Dev       Date:  2007-01-08       Impact factor: 5.578

5.  Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

Authors:  Sylvain Provot; Dawn Zinyk; Yasemin Gunes; Richa Kathri; Quynh Le; Henry M Kronenberg; Randall S Johnson; Michael T Longaker; Amato J Giaccia; Ernestina Schipani
Journal:  J Cell Biol       Date:  2007-04-30       Impact factor: 10.539
  5 in total
  27 in total

Review 1.  The role of HIF proteins in maintaining the metabolic health of the intervertebral disc.

Authors:  Elizabeth S Silagi; Ernestina Schipani; Irving M Shapiro; Makarand V Risbud
Journal:  Nat Rev Rheumatol       Date:  2021-06-03       Impact factor: 20.543

Review 2.  Transcriptional network systems in cartilage development and disease.

Authors:  Riko Nishimura; Kenji Hata; Eriko Nakamura; Tomohiko Murakami; Yoshifumi Takahata
Journal:  Histochem Cell Biol       Date:  2018-01-08       Impact factor: 4.304

Review 3.  A central role for hypoxic signaling in cartilage, bone, and hematopoiesis.

Authors:  Erinn B Rankin; Amato J Giaccia; Ernestina Schipani
Journal:  Curr Osteoporos Rep       Date:  2011-06       Impact factor: 5.096

4.  Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate.

Authors:  Qing Yao; Mohd Parvez Khan; Christophe Merceron; Edward L LaGory; Zachary Tata; Laura Mangiavini; Jiarui Hu; Krishna Vemulapalli; Navdeep S Chandel; Amato J Giaccia; Ernestina Schipani
Journal:  Dev Cell       Date:  2019-05-16       Impact factor: 12.270

5.  Deletion of clock gene Bmal1 impaired the chondrocyte function due to disruption of the HIF1α-VEGF signaling pathway.

Authors:  Zhengmin Ma; Xinxin Jin; Zhuang Qian; Fang Li; Mao Xu; Ying Zhang; Xiaomin Kang; Huixia Li; Xin Gao; Liting Zhao; Zhuanmin Zhang; Yan Zhang; Shufang Wu; Hongzhi Sun
Journal:  Cell Cycle       Date:  2019-05-26       Impact factor: 4.534

Review 6.  HIF targets in bone remodeling and metastatic disease.

Authors:  Rachelle W Johnson; Ernestina Schipani; Amato J Giaccia
Journal:  Pharmacol Ther       Date:  2015-02-12       Impact factor: 12.310

7.  Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis.

Authors:  Hidenori Matsubara; Daniel E Hogan; Elise F Morgan; Douglas P Mortlock; Thomas A Einhorn; Louis C Gerstenfeld
Journal:  Bone       Date:  2012-02-25       Impact factor: 4.398

8.  Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.

Authors:  Ellinoora Aro; Richa Khatri; Rita Gerard-O'Riley; Laura Mangiavini; Johanna Myllyharju; Ernestina Schipani
Journal:  J Biol Chem       Date:  2012-08-28       Impact factor: 5.157

9.  A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type.

Authors:  Krista A Geister; Michelle L Brinkmeier; Minnie Hsieh; Susan M Faust; I Jill Karolyi; Joseph E Perosky; Kenneth M Kozloff; Marco Conti; Sally A Camper
Journal:  Hum Mol Genet       Date:  2012-10-12       Impact factor: 6.150

Review 10.  HIF-1α and growth plate development: what we really know.

Authors:  Ernestina Schipani; Laura Mangiavini; Christophe Merceron
Journal:  Bonekey Rep       Date:  2015-08-12
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