Fibro-osseous lesions associated with simple bone cysts: three case reports and review of the literature.

An uncommon association between simple bone cyst and fibro-osseous lesions has been reported in the Literature. Here we report three additional cases, including two related to florid cemento-osseous dysplasia and one with fibrous dysplasia. All patients were African-American women, with a mean age of 39.7 years. The treatment of choice for the simple bone cyst was curettage to cause bleeding into the empty cavity. After 18 months, there was a recurrence of the cyst associated with fibrous dysplasia and a second intervention was necessary. One patient has been lost to follow-up and the other patients are currently asymptomatic. In conclusion, we describe a rare association between simple bone cyst and fibro-osseous lesions. Knowledge of this association is important for correct diagnosis and patient approach.