| Literature DB >> 21215937 |
Abstract
Recent work shows that the transcriptional coactivator Yorkie, which is negatively regulated by the Hippo tumor suppressor pathway, promotes the transcription of the proto-oncogene Myc and requires Myc function to drive growth. In turn, Myc keeps the concentration of Yorkie in check via negative feedback regulation.Entities:
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Year: 2011 PMID： 21215937 DOI： 10.1016/j.cub.2010.11.057
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834