Literature DB >> 21215364

Mitochondrial stress signals revise an old aging theory.

Dong Kyun Woo1, Gerald S Shadel.   

Abstract

In this issue, Durieux et al. (2011) describe a tissue-specific signal, originating from mitochondria, that acts cell non-autonomously to regulate life span in the nematode, C. elegans. This new finding provides a first step toward resolving the relative contributions of mitochondrial free radical damage and signaling mechanisms in aging. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21215364     DOI： 10.1016/j.cell.2010.12.023

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  29 in total

1.  Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".

Authors:  Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Zhao Lin; Stephanos Pavlides; Diana Whitaker-Menezes; Richard G Pestell; Anthony Howell; Federica Sotgia
Journal:  Cell Cycle       Date:  2011-08-01       Impact factor: 4.534

2.  Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells.

Authors:  Rui Zhao; Qianyun Yu; Long Hou; Xiaoqing Dong; Hai Zhang; Xiaoling Chen; Zhihan Zhou; Jing Ma; Shile Huang; Long Chen
Journal:  Int J Biochem Cell Biol       Date:  2020-02-05       Impact factor: 5.085

3.  Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.

Authors:  Renee M Balliet; Claudia Capparelli; Carmela Guido; Timothy G Pestell; Ubaldo E Martinez-Outschoorn; Zhao Lin; Diana Whitaker-Menezes; Barbara Chiavarina; Richard G Pestell; Anthony Howell; Federica Sotgia; Michael P Lisanti
Journal:  Cell Cycle       Date:  2011-12-01       Impact factor: 4.534

4.  The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.

Authors:  Changhan Lee; Jennifer Zeng; Brian G Drew; Tamer Sallam; Alejandro Martin-Montalvo; Junxiang Wan; Su-Jeong Kim; Hemal Mehta; Andrea L Hevener; Rafael de Cabo; Pinchas Cohen
Journal:  Cell Metab       Date:  2015-03-03       Impact factor: 27.287

5.  Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway.

Authors:  Ruijie Zhang; Nana Zhang; Hai Zhang; Chunxiao Liu; Xiaoqing Dong; Xiaoxue Wang; Yu Zhu; Chong Xu; Lei Liu; Sijun Yang; Shile Huang; Long Chen
Journal:  Br J Pharmacol       Date:  2016-11-21       Impact factor: 8.739

Review 6.  MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.

Authors:  Bérénice A Benayoun; Changhan Lee
Journal:  Bioessays       Date:  2019-08-05       Impact factor: 4.345

7.  N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain.

Authors:  Sujuan Chen; Qian Ren; Jinfei Zhang; Yangjing Ye; Zhen Zhang; Yijiao Xu; Min Guo; Haiyan Ji; Chong Xu; Chenjian Gu; Wei Gao; Shile Huang; Long Chen
Journal:  Neuropathol Appl Neurobiol       Date:  2014-10       Impact factor: 8.090

8.  Humanin: a harbinger of mitochondrial-derived peptides?

Authors:  Changhan Lee; Kelvin Yen; Pinchas Cohen
Journal:  Trends Endocrinol Metab       Date:  2013-02-08       Impact factor: 12.015

9.  Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease.

Authors:  Zhiyin Xun; Sulay Rivera-Sánchez; Sylvette Ayala-Peña; James Lim; Helen Budworth; Erin M Skoda; Paul D Robbins; Laura J Niedernhofer; Peter Wipf; Cynthia T McMurray
Journal:  Cell Rep       Date:  2012-11-01       Impact factor: 9.423

10.  Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.

Authors:  Chong Xu; Xiaoxue Wang; Yu Zhu; Xiaoqing Dong; Chunxiao Liu; Hai Zhang; Lei Liu; Shile Huang; Long Chen
Journal:  Neuropharmacology       Date:  2016-01-22       Impact factor: 5.250
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