AIM: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates. METHODS AND RESULTS: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation. CONCLUSIONS: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two. SIGNIFICANCE AND IMPACT OF THE STUDY: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.
AIM: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates. METHODS AND RESULTS: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation. CONCLUSIONS: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two. SIGNIFICANCE AND IMPACT OF THE STUDY: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.
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Authors: Jordy P M Coolen; Andreas Sjödin; Boulos Maraha; Gerard F Hajer; Mats Forsman; Ellen Verspui; Hendrina M E Frenay; Daan W Notermans; Maaike C de Vries; Frans A G Reubsaet; Armand Paauw; Guus Roeselers Journal: Stand Genomic Sci Date: 2013-08-10
Authors: Jaime Ariza-Miguel; Anders Johansson; María Isabel Fernández-Natal; Carmen Martínez-Nistal; Antonio Orduña; Elías F Rodríguez-Ferri; Marta Hernández; David Rodríguez-Lázaro Journal: Emerg Infect Dis Date: 2014-05 Impact factor: 6.883
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