Literature DB >> 21214365

DBCAT: database of CpG islands and analytical tools for identifying comprehensive methylation profiles in cancer cells.

Hsien-Chi Kuo1, Po-Yu Lin, Ting-Chiun Chung, Chin-Mei Chao, Liang-Chuan Lai, Mong-Hsun Tsai, Eric Y Chuang.   

Abstract

DBCAT (database of CpG islands and analytical tools, http://dbcat.cgm.ntu.edu.tw/ ), developed to characterize comprehensive DNA methylation profiles in human cancers, is a web-based application and methylation database containing several convenient tools for investigating epigenetic regulation in human diseases. To our knowledge, DBCAT is the first online methylation analytical tool, and is composed of three parts: a CpG island finder, a genome query browser, and a tool for analyzing methylation microarray data. The analytical tools can quickly identify genes with methylated regions from microarray data, compare the methylation status changes between different arrays, and provide functional analysis in addition to colocalizing transcription factor binding sites.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21214365     DOI： 10.1089/cmb.2010.0038

Source DB:  PubMed          Journal:  J Comput Biol        ISSN： 1066-5277            Impact factor:   1.479


  14 in total

1.  Comprehensive strategy for the design of precision drugs and identification of genetic signature behind proneness of the disease-a pharmacogenomic approach.

Authors:  Preethi M Iyer; S Karthikeyan; P Sanjay Kumar; P K Krishnan Namboori
Journal:  Funct Integr Genomics       Date:  2017-05-03       Impact factor: 3.410

2.  Transcriptional programs that control expression of the autoimmune regulator gene Aire.

Authors:  Yonatan Herzig; Shir Nevo; Chamutal Bornstein; Miriam R Brezis; Sharon Ben-Hur; Aya Shkedy; Michal Eisenberg-Bord; Ben Levi; Michael Delacher; Yael Goldfarb; Eyal David; Leehee Weinberger; Sergey Viukov; Shifra Ben-Dor; Matthieu Giraud; Jacob H Hanna; Achim Breiling; Frank Lyko; Ido Amit; Markus Feuerer; Jakub Abramson
Journal:  Nat Immunol       Date:  2016-12-12       Impact factor: 25.606

3.  Matrix stiffness epigenetically regulates the oncogenic activation of the Yes-associated protein in gastric cancer.

Authors:  Minjeong Jang; Jinhyeon An; Seung Won Oh; Joo Yeon Lim; Joon Kim; Jung Kyoon Choi; Jae-Ho Cheong; Pilnam Kim
Journal:  Nat Biomed Eng       Date:  2020-12-07       Impact factor: 25.671

4.  Expression of DOCK10.1 protein revealed with a specific antiserum: insights into regulation of first exon isoforms of DOCK10.

Authors:  Antonio Parrado
Journal:  Mol Biol Rep       Date:  2020-02-29       Impact factor: 2.316

Review 5.  Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications.

Authors:  Itika Arora; Trygve O Tollefsbol
Journal:  Methods       Date:  2020-09-14       Impact factor: 3.608

6.  CpGislandEVO: a database and genome browser for comparative evolutionary genomics of CpG islands.

Authors:  Guillermo Barturen; Stefanie Geisen; Francisco Dios; E J Maarten Hamberg; Michael Hackenberg; José L Oliver
Journal:  Biomed Res Int       Date:  2013-09-25       Impact factor: 3.411

7.  Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases.

Authors:  Belen Alvarez-Palomo; Carme Barrot-Feixat; Helena Sarret; Jordi Requena; Montserrat Pau; Jose-Manuel Vidal-Taboada; Rafael Oliva; Josep-Lluis Ballesca; Michael J Edel; Jovita Mezquita-Pla
Journal:  Oncotarget       Date:  2019-10-08

8.  Frequent down-regulation of ABC transporter genes in prostate cancer.

Authors:  Rita Demidenko; Deividas Razanauskas; Kristina Daniunaite; Juozas Rimantas Lazutka; Feliksas Jankevicius; Sonata Jarmalaite
Journal:  BMC Cancer       Date:  2015-10-12       Impact factor: 4.430

9.  Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites.

Authors:  Annika Unger; Florian Finkernagel; Nathalie Hoffmann; Felix Neuhaus; Barbara Joos; Andrea Nist; Thorsten Stiewe; Alexander Visekruna; Uwe Wagner; Silke Reinartz; Sabine Müller-Brüsselbach; Rolf Müller; Till Adhikary
Journal:  Front Immunol       Date:  2018-06-27       Impact factor: 7.561

10.  Survivin polymorphisms and susceptibility to prostate cancer: A genetic association study and an in silico analysis.

Authors:  Mohammad Karimian; Younes Aftabi; Tahereh Mazoochi; Faezeh Babaei; Tahereh Khamechian; Hossein Boojari; Hossein Nikzad
Journal:  EXCLI J       Date:  2018-05-18       Impact factor: 4.068
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.