Literature DB >> 21211775

HGPS-derived iPSCs for the ages.

Tom Misteli1.   

Abstract

In this issue of Cell Stem Cell, Zhang et al. (2011) generate patient-derived iPSCs for one of the major premature aging diseases, Hutchinson-Gilford Progeria Syndrome (HGPS). These cells are a much-needed new tool to study HGPS, and their use may lead to novel insights into mechanisms of aging. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21211775      PMCID： PMC6317067          DOI： 10.1016/j.stem.2010.12.014

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  2 in total

1.  Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells.

Authors:  Alexander M Aliper; Antonei Benjamin Csoka; Anton Buzdin; Tomasz Jetka; Sergey Roumiantsev; Alexy Moskalev; Alex Zhavoronkov
Journal:  Aging (Albany NY)       Date:  2015-01       Impact factor: 5.682

2.  Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature aging.

Authors:  Stefania Petrini; Rossella Borghi; Valentina D'Oria; Fabrizia Restaldi; Sandra Moreno; Antonio Novelli; Enrico Bertini; Claudia Compagnucci
Journal:  Aging (Albany NY)       Date:  2017-05-31       Impact factor: 5.682
  2 in total

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