Literature DB >> 21211774

Aging by telomere loss can be reversed.

Bruno Bernardes de Jesus1, Maria A Blasco.   

Abstract

Recently in Nature, Jaskelioff et al. (2010) demonstrated that multiple aging phenotypes in a mouse model of accelerated telomere loss can be reversed within 4 weeks of reactivating telomerase. This raises the major question of whether physiological aging, likely caused by a combination of molecular defects, may also be reversible. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21211774     DOI： 10.1016/j.stem.2010.12.013

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  7 in total

Review 1.  How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer.

Authors:  Yiming Lu; Bohua Wei; Tao Zhang; Zi Chen; Jing Ye
Journal:  Protein Cell       Date:  2013-07-18       Impact factor: 14.870

2.  Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.

Authors:  John Ramunas; Eduard Yakubov; Jennifer J Brady; Stéphane Y Corbel; Colin Holbrook; Moritz Brandt; Jonathan Stein; Juan G Santiago; John P Cooke; Helen M Blau
Journal:  FASEB J       Date:  2015-01-22       Impact factor: 5.191

Review 3.  Physical activity, a modulator of aging through effects on telomere biology.

Authors:  Maria Donatella Semeraro; Cassandra Smith; Melanie Kaiser; Itamar Levinger; Gustavo Duque; Hans-Juergen Gruber; Markus Herrmann
Journal:  Aging (Albany NY)       Date:  2020-06-23       Impact factor: 5.682

Review 4.  Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives.

Authors:  Alexander Vaiserman; Dmytro Krasnienkov
Journal:  Front Genet       Date:  2021-01-21       Impact factor: 4.599

Review 5.  Age-Related Pathways in Cardiac Regeneration: A Role for lncRNAs?

Authors:  Francisco Santos; Magda Correia; Sandrina Nóbrega-Pereira; Bruno Bernardes de Jesus
Journal:  Front Physiol       Date:  2021-01-20       Impact factor: 4.566

Review 6.  Is There an Interconnection between Epithelial-Mesenchymal Transition (EMT) and Telomere Shortening in Aging?

Authors:  Siti A M Imran; Muhammad Dain Yazid; Ruszymah Bt Hj Idrus; Manira Maarof; Abid Nordin; Rabiatul Adawiyah Razali; Yogeswaran Lokanathan
Journal:  Int J Mol Sci       Date:  2021-04-09       Impact factor: 5.923

7.  Increased telomere length and proliferative potential in peripheral blood mononuclear cells of adults of different ages stimulated with concanavalin A.

Authors:  Blanca Murillo-Ortiz; Froylán Albarrán-Tamayo; Sergio López-Briones; Sandra Martínez-Garza; Luis Benítez-Bribiesca; Diego Arenas-Aranda
Journal:  BMC Geriatr       Date:  2013-09-24       Impact factor: 3.921
  7 in total

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