Literature DB >> 21211112

Safe application of mitomycin C within the nasal cavity.

T Gutierrez1, C Hopkins.   

Abstract

OBJECTIVE: To describe a novel technique of delivering mitomycin C safely via endoscopic sinus surgery. CASE REPORT: Mitomycin C was applied in the median frontal drainage pathway of a 44-year-old woman suffering from recalcitrant chronic frontal sinusitis. The mitomycin C was soaked onto a neurosurgical patty, which was delivered through a nasopharyngeal tube trimmed to ensure delivery directly to the desired area, thus sparing adjacent mucosa.
CONCLUSIONS: Mitomycin C has been suggested to have a useful role in reducing post-operative scarring after endonasal surgery. The long term safety of topical mitomycin C is not yet known, and inadvertent topical application to adjacent mucosa should be avoided. The described technique achieves this in a simple manner, and can be easily applied to other locations.

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Year:  2011        PMID: 21211112     DOI: 10.1017/S0022215110002665

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  2 in total

Review 1.  Comprehensive review on endonasal endoscopic sinus surgery.

Authors:  Rainer K Weber; Werner Hosemann
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2015-12-22

2.  Endoscopic agger nasi type Draf IIb treatment for frontal sinus lesions.

Authors:  Linggai Shi; Jun Liu; Jiqing Ma; Fei Liu; Guangke Wang
Journal:  Exp Ther Med       Date:  2016-06-17       Impact factor: 2.447

  2 in total

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