Literature DB >> 21207023

Intraosseous hibernoma.

Rajendra Kumar1, Michael T Deaver, Bogdan A Czerniak, John E Madewell.   

Abstract

We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.

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Year:  2011        PMID: 21207023     DOI: 10.1007/s00256-010-1079-x

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  15 in total

Review 1.  Morphological studies on brown adipose tissue in the bat and in humans of various ages.

Authors:  T Ito; Y Tanuma; M Yamada; M Yamamoto
Journal:  Arch Histol Cytol       Date:  1991-03

2.  MR imaging findings in hibernoma.

Authors:  S Peer; R Kühberger; A Dessl; W Judmaier
Journal:  Skeletal Radiol       Date:  1997-08       Impact factor: 2.199

3.  Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases.

Authors:  Nirmala A Jambhekar; Bharat Rekhi; Kiran Thorat; Rajesh Dikshit; Manish Agrawal; Ajay Puri
Journal:  Arch Pathol Lab Med       Date:  2010-08       Impact factor: 5.534

4.  Malignant tumor of brown fat in patient with Turner's syndrome.

Authors:  W S Lowry; P B Halmos
Journal:  Br Med J       Date:  1967-12-23

5.  Hibernoma: imaging characteristics of a rare benign soft tissue tumor.

Authors:  S E Anderson; C Schwab; E Stauffer; A Banic; L S Steinbach
Journal:  Skeletal Radiol       Date:  2001-10       Impact factor: 2.199

6.  The morphologic spectrum of hibernoma: a clinicopathologic study of 170 cases.

Authors:  M A Furlong; J C Fanburg-Smith; M Miettinen
Journal:  Am J Surg Pathol       Date:  2001-06       Impact factor: 6.394

Review 7.  MR and CT findings in a case of hibernoma of the thigh extending into the pelvis.

Authors:  T Mugel; M A Ghossain; C Guinet; J Buy; J Bethoux; P Texier; D Vadrot
Journal:  Eur Radiol       Date:  1998       Impact factor: 5.315

8.  Hibernoma: distinctive light and electron microscopic features and relationship to brown adipose tissue.

Authors:  E F Gaffney; H K Hargreaves; E Semple; F Vellios
Journal:  Hum Pathol       Date:  1983-08       Impact factor: 3.466

9.  CT and MR characteristics of hibernoma: six cases.

Authors:  Memduh Dursun; Ayaz Agayev; Baris Bakir; Harzem Ozger; Levent Eralp; Mustafa Sirvanci; Koray Guven; Mehtap Tunaci
Journal:  Clin Imaging       Date:  2008 Jan-Feb       Impact factor: 1.605

10.  Hibernoma: 18F FDG PET/CT imaging.

Authors:  Rathan M Subramaniam; Amy C Clayton; Dimitrios Karantanis; Douglas A Collins
Journal:  J Thorac Oncol       Date:  2007-06       Impact factor: 15.609

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  12 in total

Review 1.  Quantitative proton MR techniques for measuring fat.

Authors:  H H Hu; H E Kan
Journal:  NMR Biomed       Date:  2013-10-03       Impact factor: 4.044

Review 2.  Intraosseous hibernoma: a case report and review of the literature.

Authors:  R Botchu; F Puls; Y L Hock; A M Davies; H Wafa; R J Grimer; V Bröcker; S James
Journal:  Skeletal Radiol       Date:  2013-03-10       Impact factor: 2.199

Review 3.  Brown adipose tissue and bone.

Authors:  M E Lidell; S Enerbäck
Journal:  Int J Obes Suppl       Date:  2015-08-04

4.  Intraosseous hibernoma: a rare adipocytic bone tumour.

Authors:  M Vlychou; J Teh; D Whitwell; N A Athanasou
Journal:  Skeletal Radiol       Date:  2016-09-06       Impact factor: 2.199

5.  Intraosseous hibernoma: Two case reports and a review of the literature.

Authors:  Samantha N Weiss; Ankit Mohla; Gord Guo Zhu; Christina Gutowski; Tae Won B Kim; Rohan Amin
Journal:  Radiol Case Rep       Date:  2022-05-09

6.  MRI detection of brown adipose tissue with low fat content in newborns with hypothermia.

Authors:  Houchun H Hu; Tai-Wei Wu; Larry Yin; Mimi S Kim; Jonathan M Chia; Thomas G Perkins; Vicente Gilsanz
Journal:  Magn Reson Imaging       Date:  2013-10-15       Impact factor: 2.546

Review 7.  Intraosseous hibernoma: characterization of five cases and literature review.

Authors:  S Fiona Bonar; Geoffrey Watson; Cristian Gragnaniello; Kevin Seex; John Magnussen; John Earwaker
Journal:  Skeletal Radiol       Date:  2014-04-05       Impact factor: 2.199

Review 8.  Hibernomas: a single-institution experience and review of literature.

Authors:  Corey Beals; Alan Rogers; Paul Wakely; Joel L Mayerson; Thomas J Scharschmidt
Journal:  Med Oncol       Date:  2013-11-19       Impact factor: 3.064

9.  Intraosseous Hibernoma: A Rare and Unique Intraosseous Lesion.

Authors:  Boram Song; Hye Jin Ryu; Cheol Lee; Kyung Chul Moon
Journal:  J Pathol Transl Med       Date:  2017-08-22

10.  Rare case of a radiographically occult sacral lesion detected on MRI presenting with intractable back pain.

Authors:  A J Degnan; C Maldjian; L Pantanowitz; J K Kofler
Journal:  BJR Case Rep       Date:  2015-05-26
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