R Guruswamy1, Pankaj Relan, Sumant Khanna. 1. R. GURUSWAMY, Consultant Psychiatrist, St. Jude's Hospital, V /Foil, St Lucia, P.O. Box 331, West Indies.
Abstract
OBJECTIVE: The current study aims to replicate western reports of a familial excess of syndromal and sub-syndromal Obsessive Compulsive Disorder (OCD) in OCD probands in an Indian population. METHOD: 148 relatives of OCD probands were compared with 151 normal subjects, based on evaluation on Schedule for Clinical Assessment for Neuropsychiatry (SCAN). RESULTS: There were no clinically significant differences in the prevalence of psychiatric disorders between the two samples. CONCLUSION: In an Indian setting, the absence of familial loading in adult OCD is being reported. Whether subgroups of OCD are familial, or other factors play a role in the pathogenesis of OCD in India needs to be explored.
OBJECTIVE: The current study aims to replicate western reports of a familial excess of syndromal and sub-syndromal Obsessive Compulsive Disorder (OCD) in OCD probands in an Indian population. METHOD: 148 relatives of OCD probands were compared with 151 normal subjects, based on evaluation on Schedule for Clinical Assessment for Neuropsychiatry (SCAN). RESULTS: There were no clinically significant differences in the prevalence of psychiatric disorders between the two samples. CONCLUSION: In an Indian setting, the absence of familial loading in adult OCD is being reported. Whether subgroups of OCD are familial, or other factors play a role in the pathogenesis of OCD in India needs to be explored.
Entities:
Keywords:
Adult Obsessive Compulsive Diorder; Genetics; India
Authors: G Nestadt; J Samuels; M A Riddle; K Y Liang; O J Bienvenu; R Hoehn-Saric; M Grados; B Cullen Journal: Psychol Med Date: 2001-04 Impact factor: 7.723
Authors: G Nestadt; J Samuels; M Riddle; O J Bienvenu; K Y Liang; M LaBuda; J Walkup; M Grados; R Hoehn-Saric Journal: Arch Gen Psychiatry Date: 2000-04